PCLO 抗体 (PE)
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- 抗原 See all PCLO 抗体
- PCLO (Piccolo (Presynaptic Cytomatrix Protein) (PCLO))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PCLO antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS)
- 特异性
- The mouse monoclonal antibody PCLO-01 recognizes PCLO (Piccolo), a more than 400 kDa multidomain protein expressed mainly in the presynaptic cytoplasmatic matrix of the neurons.
- 交叉反应 (详细)
- Human
- 纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- 免疫原
- Human recombinant PCLO protein
- 克隆位点
- PCLO-01
- 亚型
- IgG1
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- 应用备注
- Flow cytometry: Recommended dilution: 1-5 μg/mL. Intracellular staining.
- 说明
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The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
- 限制
- 仅限研究用
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- 浓度
- 0.1 mg/mL
- 缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- 抗原
- PCLO (Piccolo (Presynaptic Cytomatrix Protein) (PCLO))
- 别名
- PCLO (PCLO 产品)
- 别名
- pclo antibody, wu:fj53e09 antibody, Acz antibody, Pico antibody, mKIAA0559 antibody, aczonin antibody, PCLO antibody, ACZ antibody, piccolo presynaptic cytomatrix protein antibody, piccolo presynaptic cytomatrix protein a antibody, piccolo (presynaptic cytomatrix protein) antibody, PCLO antibody, pcloa antibody, Pclo antibody, LOC768552 antibody
- 背景
- Piccolo presynaptic cytomatrix protein,PCLO (piccolo, also known as aczonin) is a large (more than 400 kDa) multidomain protein of the presynaptic cytomatrix in neurons, that is present in all vertebrate synapses, but is absent from invertebrates. It contains zinc finger and coiled-coil sequences, as well as N-terminal glutamine-rich sequence, and C-terminal PDZ domain followed by two C2 domains (C2A and C2B). In vitro binding and transfection experiments suggested that PCLO binds to multiple proteins including profilin and L-type calcium channels. It is involved in neurotransmitter release and insulin secretion.,ACZ, PCH3, piccolo, aczonin
- 基因ID
- 27445
- UniProt
- Q9Y6V0
- 途径
- Hormone Transport, Synaptic Vesicle Exocytosis
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