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PCLO 抗体 (PE)

PCLO 适用: 人 FACS 宿主: 小鼠 Monoclonal PCLO-01 PE
产品编号 ABIN2749163
发货至: 中国
  • 抗原 See all PCLO 抗体
    PCLO (Piccolo (Presynaptic Cytomatrix Protein) (PCLO))
    适用
    • 7
    • 1
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    • 1
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    • 1
    宿主
    • 6
    • 1
    小鼠
    克隆类型
    • 4
    • 3
    单克隆
    标记
    • 6
    • 1
    This PCLO antibody is conjugated to PE
    应用范围
    • 7
    • 3
    • 1
    Flow Cytometry (FACS)
    特异性
    The mouse monoclonal antibody PCLO-01 recognizes PCLO (Piccolo), a more than 400 kDa multidomain protein expressed mainly in the presynaptic cytoplasmatic matrix of the neurons.
    交叉反应 (详细)
    Human
    纯化方法
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    免疫原
    Human recombinant PCLO protein
    克隆位点
    PCLO-01
    亚型
    IgG1
  • 应用备注
    Flow cytometry: Recommended dilution: 1-5 μg/mL. Intracellular staining.
    说明

    The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.

    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原
    PCLO (Piccolo (Presynaptic Cytomatrix Protein) (PCLO))
    别名
    PCLO (PCLO 产品)
    别名
    pclo antibody, wu:fj53e09 antibody, Acz antibody, Pico antibody, mKIAA0559 antibody, aczonin antibody, PCLO antibody, ACZ antibody, piccolo presynaptic cytomatrix protein antibody, piccolo presynaptic cytomatrix protein a antibody, piccolo (presynaptic cytomatrix protein) antibody, PCLO antibody, pcloa antibody, Pclo antibody, LOC768552 antibody
    背景
    Piccolo presynaptic cytomatrix protein,PCLO (piccolo, also known as aczonin) is a large (more than 400 kDa) multidomain protein of the presynaptic cytomatrix in neurons, that is present in all vertebrate synapses, but is absent from invertebrates. It contains zinc finger and coiled-coil sequences, as well as N-terminal glutamine-rich sequence, and C-terminal PDZ domain followed by two C2 domains (C2A and C2B). In vitro binding and transfection experiments suggested that PCLO binds to multiple proteins including profilin and L-type calcium channels. It is involved in neurotransmitter release and insulin secretion.,ACZ, PCH3, piccolo, aczonin
    基因ID
    27445
    UniProt
    Q9Y6V0
    途径
    Hormone Transport, Synaptic Vesicle Exocytosis
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