Myeloperoxidase 抗体 (FITC)
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- 抗原 See all Myeloperoxidase (MPO) 抗体
- Myeloperoxidase (MPO)
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Myeloperoxidase antibody is conjugated to FITC
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应用范围
- Flow Cytometry (FACS)
- 特异性
- The mouse monoclonal antibody MPO421-8B2 recognizes human myeloperoxidase, a heme protein present in intracellular granules of myeloblasts, neutrophils and monocytes. It is a marker of acute myelogenous leukemias and acute lymphoblastic leukemias.
- 交叉反应 (详细)
- Human
- 纯化方法
- Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- 免疫原
- Human myeloperoxidase
- 克隆位点
- MPO421-8B2
- 亚型
- IgG1
- Top Product
- Discover our top product MPO Primary Antibody
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- 应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. Intracellular staining.
- 说明
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The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.
- 限制
- 仅限研究用
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- 缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- 抗原
- Myeloperoxidase (MPO)
- Abstract
- MPO 产品
- 别名
- mKIAA4033 antibody, MPO antibody, LOC100335032 antibody, POX2' antibody, XPOX2' antibody, mpo antibody, mpo-A antibody, pmr-1 antibody, pmr1 antibody, pox2 antibody, xpox2 antibody, myeloperoxidase antibody, myeloperoxidase L homeolog antibody, MPO antibody, Mpo antibody, LOC100335032 antibody, mpo.L antibody
- 背景
- Myeloperoxidase,Myeloperoxidase (MPO) is a heme enzyme that is localized in azurophilic (primary) granules of myeloid cells and its synthesis occurs at an early stage of differentiation. The mature myeloperoxidase is a tetramer composed of two light (12 kDa) and two heavy (60 kDa) chains. This enzyme uses hydrogen peroxide to oxidize numerous substrates, including serotonin, melatonin or chloride, to produce reactive free radicals that contribute to immune reactions of myeloid cells against pathogens. Myeloperoxidase functions not only in host defense by mediating efficient microbial killing but also can contribute to progressive tissue damage in chronic inflammatory states such as atherosclerosis or acute pancreatitis.,MPO
- 基因ID
- 4353
- UniProt
- P05164
- 途径
- Chromatin Binding
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