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SLAMF1 抗体 (PE)

SLAMF1 适用: 人 FACS 宿主: 小鼠 Monoclonal SLAM-4 PE
产品编号 ABIN2749109
发货至: 中国
  • 抗原 See all SLAMF1 抗体
    SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This SLAMF1 antibody is conjugated to PE
    应用范围
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    Flow Cytometry (FACS)
    特异性
    The mouse monoclonal antibody SLAM.4 recognizes an extracellular epitope of CD150, a cell surface molecule expressed on lymphocytes and involved in their activation.
    交叉反应 (详细)
    Human
    纯化方法
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    免疫原
    Human CD150-transfected 300.19 cells
    克隆位点
    SLAM-4
    亚型
    IgG1
    Top Product
    Discover our top product SLAMF1 Primary Antibody
  • 应用备注
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    说明

    The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    限制
    仅限研究用
  • 缓冲液
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Romero, Zapater, Calvo, Kalko, de la Fuente, Tovar, Ockeloen, Pizcueta, Engel: "CD229 (Ly9) lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological synapse." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 11, pp. 7033-42, (2005) (PubMed).

    Romero, Benítez, March, Vilella, Miralpeix, Engel: "Differential expression of SAP and EAT-2-binding leukocyte cell-surface molecules CD84, CD150 (SLAM), CD229 (Ly9) and CD244 (2B4)." in: Tissue antigens, Vol. 64, Issue 2, pp. 132-44, (2004) (PubMed).

  • 抗原
    SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))
    别名
    CD150 (SLAMF1 产品)
    别名
    CD150 antibody, SLAM antibody, SLAMF1 antibody, 4933415F16 antibody, AA177906 antibody, CDw150 antibody, ESTM51 antibody, IPO-3 antibody, Slam antibody, RGD1560634 antibody, signaling lymphocytic activation molecule family member 1 antibody, SLAMF1 antibody, Slamf1 antibody
    背景
    Signaling lymphocytic activation molecule family m,CD150, also known as SLAM (signaling lymphocyte activation molecule) is a 70-95 kDa single chain transmembrane phosphoglycoprotein of the CD2 family. Its extracellular part contains eight potential N-glycosylation sites, and the intracellular tail contains three unique tyrosine-based motifs. These binding sites can be recognized by SH2-binding phosphatases and the adaptor proteins, such as SAP/SH2D1A or EAT-2. The SLAM family receptors are involved in leucocyte activation and contribute to the effective germinal center formation, generation of high-affinity antibody-secreting plasma cells, and memory T and B cells, thereby facilitating long-term immune response. CD150 expression is upregulated after cell activation.,SLAM, SLAMF1
    基因ID
    6504
    UniProt
    Q13291
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