(3 references)-
- 抗原 See all IL3RA 抗体
- IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This IL3RA antibody is conjugated to FITC
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应用范围
- Flow Cytometry (FACS)
- 特异性
- The mouse monoclonal antibody 6H6 recognizes an extracellular epitope of CD123 (interleukin 3 receptor alpha), a 60-70 kDa transmembrane protein expressed by myeloid precursors, megakaryocytes, macrophages, dendritic cells, mast cells, basophils, and some B cells. This antibody does not inhibit IL-3 binding to its receptor.
- 交叉反应 （详细）
- Human
- 纯化方法
- Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- 免疫原
- IL3 receptor alpha chain expressed on the surface of transiently transfected COS cells
- 克隆位点
- 6H6
- 亚型
- IgG1
- Top Product
- Discover our top product IL3RA Primary Antibody
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anti-Interleukin 3 Receptor, alpha (IL3RA) (AA 200-305) antibody
IL3RA 适用: 人 FACS, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 8E11C5 unconjugated
anti-Interleukin 3 Receptor, alpha (IL3RA) (AA 26-171) antibodyIL3RA 适用: 人 IHC, ISt, StM 宿主: 小鼠 Monoclonal IL3RA-1531 unconjugated
anti-Interleukin 3 Receptor, alpha (IL3RA) antibody (PE)IL3RA 适用: 人 FACS 宿主: 小鼠 Monoclonal 6H6 PE
anti-Interleukin 3 Receptor, alpha (IL3RA) (AA 19-158) antibodyIL3RA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 3 Receptor, alpha (IL3RA) (AA 201-300) antibodyIL3RA 适用: 人, 小鼠 FACS, WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 3 Receptor, alpha (IL3RA) (AA 167-331) antibodyIL3RA 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 3 Receptor, alpha (IL3RA) (AA 26-171) antibodyIL3RA 适用: 人 IHC, ELISA, ISt, StM, Coat 宿主: 兔 Monoclonal IL3RA-2947R unconjugated Recombinant Antibody
anti-Interleukin 3 Receptor, alpha (IL3RA) antibodyIL3RA 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 3 Receptor, alpha (IL3RA) antibodyIL3RA 适用: 人 FACS, WB, IP, IHC (fro) 宿主: 小鼠 Monoclonal 6H6 unconjugated
anti-Interleukin 3 Receptor, alpha (IL3RA) (AA 19-305) antibodyIL3RA 适用: 人 FACS, ELISA 宿主: 兔 Monoclonal DM31 unconjugated
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- 应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
- 说明
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The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.
- 限制
- 仅限研究用
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- 缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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: "Plasmacytoid dendritic cells resident in human thymus drive natural Treg cell development." in: Blood, Vol. 115, Issue 26, pp. 5366-75, (2010) (PubMed).
: "TCL1 expression in plasmacytoid dendritic cells (DC2s) and the related CD4+ CD56+ blastic tumors of skin." in: Blood, Vol. 101, Issue 12, pp. 5007-9, (2003) (PubMed).
: "Monoclonal antibody 7G3 recognizes the N-terminal domain of the human interleukin-3 (IL-3) receptor alpha-chain and functions as a specific IL-3 receptor antagonist." in: Blood, Vol. 87, Issue 1, pp. 83-92, (1996) (PubMed).
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: "Plasmacytoid dendritic cells resident in human thymus drive natural Treg cell development." in: Blood, Vol. 115, Issue 26, pp. 5366-75, (2010) (PubMed).
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- 抗原
- IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
- 别名
- CD123 (IL3RA 产品)
- 别名
- CD123 antibody, IL3R antibody, IL3RAY antibody, IL3RX antibody, IL3RY antibody, hIL-3Ra antibody, CDw123 antibody, SUT-1 antibody, Cyrl antibody, interleukin 3 receptor subunit alpha antibody, interleukin 3 receptor, alpha chain antibody, IL3RA antibody, Il3ra antibody
- 背景
- Interleukin 3 receptor subunit alpha,CD123 is the alpha chain of interleukin 3 receptor (IL-3R alpha). This subunit heterodimerizes with the interleukin 3 receptor beta chain (CD131), which is shared with other receptors. CD123 interacts with IL-3 specifically, but with low affinity, and association with the beta subunit confers high affinity binding to the receptor heterodimer. Both chains are required for signaling, but receptor activation and signal transduction depend on IL-3 binding to CD123 as the initial step.,IL3RA, MGC34174, hIL-3Ra
- 基因ID
- 3563
- UniProt
- P26951
- 途径
- JAK/STAT Signaling
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