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CD235a/GYPA 抗体

GYPA 适用: 人, 大鼠 FACS, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal JC159 unconjugated
产品编号 ABIN2749051
发货至: 中国
  • 抗原 See all CD235a/GYPA (GYPA) 抗体
    CD235a/GYPA (GYPA) (Glycophorin A (GYPA))
    适用
    • 131
    • 17
    • 12
    • 8
    人, 大鼠
    宿主
    • 74
    • 63
    • 10
    • 1
    小鼠
    克隆类型
    • 85
    • 61
    单克隆
    标记
    • 56
    • 17
    • 11
    • 10
    • 5
    • 3
    • 3
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    • 2
    • 2
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    • 2
    • 1
    • 1
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    This CD235a/GYPA antibody is un-conjugated
    应用范围
    • 98
    • 54
    • 42
    • 33
    • 24
    • 22
    • 15
    • 13
    • 13
    • 13
    • 11
    • 5
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    Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    The mouse monoclonal antibody JC159 recognizes an epitope between amino acids 27 and 40 of the extracellular portion of CD235a (glycophorin A), a sialoglycoprotein expressed on early erythroblasts, late erythroblasts, erythroblasts, mature erythrocytes and the cells of erythroid cell lines K562 and HEL. The antibody does not react with glycophorin B.
    交叉反应 (详细)
    Human, Rat
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    Membrane preparation from splenic hairy cell leukemia
    克隆位点
    JC159
    亚型
    IgG1
    Top Product
    Discover our top product GYPA Primary Antibody
  • 应用备注
    Immunohistochemistry (paraffin sections): Recommended dilution: 10 μg/mL.
    Flow cytometry: Recommended dilution: 1-4 μg/mL
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • Beck, Jagodzinski, Eller, Thelian, Matyas, Kunz, Alving: "Platelets and erythrocyte-bound platelets bind infectious HIV-1 in plasma of chronically infected patients." in: PLoS ONE, Vol. 8, Issue 11, pp. e81002, (2013) (PubMed).

    Alijotas-Reig, Palacio-Garcia, Llurba, Vilardell-Tarres: "Cell-derived microparticles and vascular pregnancy complications: a systematic and comprehensive review." in: Fertility and sterility, Vol. 99, Issue 2, pp. 441-9, (2013) (PubMed).

    Maijenburg, Kleijer, Vermeul, Mul, van Alphen, van der Schoot, Voermans: "The composition of the mesenchymal stromal cell compartment in human bone marrow changes during development and aging." in: Haematologica, Vol. 97, Issue 2, pp. 179-83, (2012) (PubMed).

  • 抗原
    CD235a/GYPA (GYPA) (Glycophorin A (GYPA))
    别名
    CD235a (GYPA 产品)
    别名
    GYPA antibody, gpa antibody, AI853584 antibody, CD235a antibody, GPA antibody, GPErik antibody, GPSAT antibody, HGpMiV antibody, HGpMiXI antibody, HGpSta(C) antibody, MN antibody, MNS antibody, PAS-2 antibody, glycophorin A (MNS blood group) antibody, glycophorin A antibody, GYPA antibody, Gypa antibody
    背景
    Glycophorin A (MNS blood group),CD235a (glycophorin A, GPA) is a transmembrane sialoglycoprotein expressed on erythrocytes and their precursors. Similarly to CD235b (glycophorin B, GPB), these molecules provide the cells with a large mucin-like surface, which minimalizes aggregation between erythrocytes in the circulation. GPA is the carrier of blood group M and N specificities, while GPB accounts for S, s and U specificities. CD235a is a receptor of Hsa, a Streptococcus adhesin.,Glycophorin A, GYPA, GPA, PAS-2, Sialoglycoprotein alpha, MN sialoglycoprotein, GPSAT, GPErik, MSN blood group
    基因ID
    2993
    UniProt
    P02724
    途径
    Maintenance of Protein Location
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