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- 抗原 See all CD2 抗体
- CD2
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD2 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Functional Studies (Func)
- 特异性
- The mouse monoclonal antibody TS1/8 recognizes an extracellular epitope of CD2, a 50 kDa glycoprotein present on the human peripheral blood T lymphocytes and NK cells, also expressed by all thymocytes.
- 交叉反应 (详细)
- Human
- 纯化方法
- Purified by protein-A affinity chromatography.
- 纯度
- > 95 % (by SDS-PAGE)
- 内毒素水平
- Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
- 免疫原
- Cytotoxic T lymphocytes
- 克隆位点
- TS1-8
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product CD2 Primary Antibody
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- 应用备注
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Functional application: Blocking.
Flow cytometry: Recommended dilution: 1-4 μg/mL - 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.4
- 储存液
- Azide free
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Do not freeze.
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Tracking proliferative history in lymphocyte development with cre-mediated sister chromatid recombination." in: PLoS genetics, Vol. 9, Issue 10, pp. e1003887, (2013) (PubMed).
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Tracking proliferative history in lymphocyte development with cre-mediated sister chromatid recombination." in: PLoS genetics, Vol. 9, Issue 10, pp. e1003887, (2013) (PubMed).
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- 抗原
- CD2
- 别名
- CD2 (CD2 产品)
- 别名
- CD2 antibody, LFA-2 antibody, Ly-37 antibody, Ly37 antibody, SRBC antibody, T11 antibody, CD2R antibody, LFA2 antibody, OX-34 antibody, OX34 antibody, CD2 molecule antibody, CD2 antigen antibody, Cd2 molecule antibody, CD2 antibody, Cd2 antibody
- 背景
- CD2 Molecule,CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.,T11, LFA-2, SRBC
- 基因ID
- 914
- UniProt
- P06729
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