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CD2 抗体

CD2 适用: 人 FACS, Func 宿主: 小鼠 Monoclonal TS1-8 unconjugated
产品编号 ABIN2749021
发货至: 中国
  • 抗原 See all CD2 抗体
    CD2
    适用
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    宿主
    • 128
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    小鼠
    克隆类型
    • 153
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    单克隆
    标记
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    This CD2 antibody is un-conjugated
    应用范围
    • 142
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    Flow Cytometry (FACS), Functional Studies (Func)
    特异性
    The mouse monoclonal antibody TS1/8 recognizes an extracellular epitope of CD2, a 50 kDa glycoprotein present on the human peripheral blood T lymphocytes and NK cells, also expressed by all thymocytes.
    交叉反应 (详细)
    Human
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    内毒素水平
    Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
    免疫原
    Cytotoxic T lymphocytes
    克隆位点
    TS1-8
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD2 Primary Antibody
  • 应用备注
    Functional application: Blocking.
    Flow cytometry: Recommended dilution: 1-4 μg/mL
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4
    储存液
    Azide free
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • Zhang, Dai, Li, Zhuang: "Tracking proliferative history in lymphocyte development with cre-mediated sister chromatid recombination." in: PLoS genetics, Vol. 9, Issue 10, pp. e1003887, (2013) (PubMed).

  • 抗原
    CD2
    别名
    CD2 (CD2 产品)
    别名
    CD2 antibody, LFA-2 antibody, Ly-37 antibody, Ly37 antibody, SRBC antibody, T11 antibody, CD2R antibody, LFA2 antibody, OX-34 antibody, OX34 antibody, CD2 molecule antibody, CD2 antigen antibody, Cd2 molecule antibody, CD2 antibody, Cd2 antibody
    背景
    CD2 Molecule,CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.,T11, LFA-2, SRBC
    基因ID
    914
    UniProt
    P06729
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