PDE4D 抗体
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- 抗原 See all PDE4D 抗体
- PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PDE4D antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF), Confocal Microscopy (CM)
- 纯化方法
- Affinity Purified
- 免疫原
- Synthetic peptide selective for all PDE4D variants.
- 亚型
- IgG
- Top Product
- Discover our top product PDE4D Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.57 μg/μL
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Increase of Intracellular Cyclic AMP by PDE4 Inhibitors Affects HepG2 Cell Cycle Progression and Survival." in: Journal of cellular biochemistry, Vol. 118, Issue 6, pp. 1401-1411, (2016) (PubMed).
: "Distribution and function of 3',5'-Cyclic-AMP phosphodiesterases in the human ovary." in: Molecular and cellular endocrinology, Vol. 403, pp. 10-20, (2015) (PubMed).
: "Etazolate abrogates the lipopolysaccharide (LPS)-induced downregulation of the cAMP/pCREB/BDNF signaling, neuroinflammatory response and depressive-like behavior in mice." in: Neuroscience, Vol. 263, pp. 1-14, (2014) (PubMed).
: "Phosphodiesterase types 3 and 4 regulate the phasic contraction of neonatal rat bladder smooth myocytes via distinct mechanisms." in: Cellular signalling, Vol. 26, Issue 5, pp. 1001-10, (2014) (PubMed).
: "Presynaptic inhibition by α2 receptor/adenylate cyclase/PDE4 complex at retinal rod bipolar synapse." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 28, pp. 9432-40, (2014) (PubMed).
: "RNA interference-mediated phosphodiesterase 4D splice variants knock-down in the prefrontal cortex produces antidepressant-like and cognition-enhancing effects." in: British journal of pharmacology, Vol. 168, Issue 4, pp. 1001-14, (2013) (PubMed).
: "Attenuation of inhibitory prostaglandin E2 signaling in human lung fibroblasts is mediated by phosphodiesterase 4." in: American journal of respiratory cell and molecular biology, Vol. 47, Issue 6, pp. 729-37, (2013) (PubMed).
: "Protein implicated in nonsyndromic mental retardation regulates protein kinase A (PKA) activity." in: The Journal of biological chemistry, Vol. 287, Issue 18, pp. 14644-58, (2012) (PubMed).
: "Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis." in: Cellular signalling, Vol. 23, Issue 1, pp. 152-60, (2011) (PubMed).
: "cGMP phosphodiesterase inhibition improves the vascular and metabolic actions of insulin in skeletal muscle." in: American journal of physiology. Endocrinology and metabolism, Vol. 301, Issue 2, pp. E342-50, (2011) (PubMed).
: "NCS 613, a potent and specific PDE4 inhibitor, displays anti-inflammatory effects on human lung tissues." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 301, Issue 4, pp. L441-50, (2011) (PubMed).
: "β2-adrenergic receptor-coupled phosphoinositide 3-kinase constrains cAMP-dependent increases in cardiac inotropy through phosphodiesterase 4 activation." in: Anesthesia and analgesia, Vol. 111, Issue 4, pp. 870-7, (2010) (PubMed).
: "Anxiogenic-like behavioral phenotype of mice deficient in phosphodiesterase 4B (PDE4B)." in: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, Vol. 33, Issue 7, pp. 1611-23, (2008) (PubMed).
: "Expression profiles of phosphodiesterase 4D splicing variants in osteoblastic cells." in: Journal of bone and mineral metabolism, Vol. 26, Issue 2, pp. 152-8, (2008) (PubMed).
: "In vivo and in vitro measurement of brain phosphodiesterase 4 in rats after antidepressant administration." in: Synapse (New York, N.Y.), Vol. 61, Issue 2, pp. 78-86, (2007) (PubMed).
: "Spectrin-anchored phosphodiesterase 4D4 restricts cAMP from disrupting microtubules and inducing endothelial cell gap formation." in: Journal of cell science, Vol. 121, Issue Pt 1, pp. 110-9, (2007) (PubMed).
: "Mammalian sperm phosphodiesterases and their involvement in receptor-mediated cell signaling important for capacitation." in: Molecular reproduction and development, Vol. 71, Issue 4, pp. 495-508, (2006) (PubMed).
: "Regulation of phosphodiesterase-4 (PDE4) expression in mouse brain by repeated antidepressant treatment: comparison with rolipram." in: Brain research, Vol. 1096, Issue 1, pp. 104-12, (2006) (PubMed).
: "PGE(1) stimulation of HEK293 cells generates multiple contiguous domains with different [cAMP]: role of compartmentalized phosphodiesterases." in: The Journal of cell biology, Vol. 175, Issue 3, pp. 441-51, (2006) (PubMed).
: "Cloning and characterization of novel PDE4D isoforms PDE4D6 and PDE4D7." in: Cellular signalling, Vol. 15, Issue 9, pp. 883-91, (2004) (PubMed).
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Increase of Intracellular Cyclic AMP by PDE4 Inhibitors Affects HepG2 Cell Cycle Progression and Survival." in: Journal of cellular biochemistry, Vol. 118, Issue 6, pp. 1401-1411, (2016) (PubMed).
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- 抗原
- PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))
- 别名
- PDE4D (PDE4D 产品)
- UniProt
- Q07343
- 途径
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
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