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PDE1C 抗体 (N-Term)

PDE1C 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IF, IP, ICC, CM 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2747083
发货至: 中国
  • 抗原 See all PDE1C 抗体
    PDE1C (phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C))
    抗原表位
    • 7
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 24
    • 13
    • 13
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 24
    克隆类型
    • 24
    多克隆
    标记
    • 16
    • 4
    • 3
    • 1
    This PDE1C antibody is un-conjugated
    应用范围
    • 15
    • 11
    • 8
    • 7
    • 6
    • 6
    • 5
    • 3
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Confocal Microscopy (CM)
    纯化方法
    Affinity Purified
    免疫原
    Synthetic peptide corresponding to unique amino acid sequence on PDE1C gene.
    亚型
    IgG
    Top Product
    Discover our top product PDE1C Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.75-1.25 μg/μL
  • Cesarini, Martini, Vitiani, Gravina, Di Agostino, Graziani, DAlessandris, Pallini, Larocca, Rossi, Jannini, Dolci: "Type 5 phosphodiesterase regulates glioblastoma multiforme aggressiveness and clinical outcome." in: Oncotarget, Vol. 8, Issue 8, pp. 13223-13239, (2017) (PubMed).

    Petersen, Kristensen, Jeppesen, Grøndahl, Wissing, Macklon, Andersen: "Distribution and function of 3',5'-Cyclic-AMP phosphodiesterases in the human ovary." in: Molecular and cellular endocrinology, Vol. 403, pp. 10-20, (2015) (PubMed).

    Yougbaré, Keravis, Abusnina, Decossas, Schall, Muller, Lugnier: "Cyclic GMP catabolism up-regulation in MRL/lpr lupus-prone mice is associated with organ remodeling." in: Biochimica et biophysica acta, Vol. 1842, Issue 7, pp. 916-26, (2014) (PubMed).

    Abusnina, Keravis, Yougbaré, Bronner, Lugnier: "Anti-proliferative effect of curcumin on melanoma cells is mediated by PDE1A inhibition that regulates the epigenetic integrator UHRF1." in: Molecular nutrition & food research, Vol. 55, Issue 11, pp. 1677-89, (2012) (PubMed).

    Abusnina, Alhosin, Keravis, Muller, Fuhrmann, Bronner, Lugnier: "Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis." in: Cellular signalling, Vol. 23, Issue 1, pp. 152-60, (2011) (PubMed).

    Genders, Bradley, Rattigan, Richards: "cGMP phosphodiesterase inhibition improves the vascular and metabolic actions of insulin in skeletal muscle." in: American journal of physiology. Endocrinology and metabolism, Vol. 301, Issue 2, pp. E342-50, (2011) (PubMed).

    Dong, Zitt, Auriga, Hatzelmann, Epstein: "Inhibition of PDE3, PDE4 and PDE7 potentiates glucocorticoid-induced apoptosis and overcomes glucocorticoid resistance in CEM T leukemic cells." in: Biochemical pharmacology, Vol. 79, Issue 3, pp. 321-9, (2009) (PubMed).

    Deplano, Giorgi, Maccarone, Santone, Nuccetelli, Basso, Bisti: "Gene expression and protein localization of calmodulin-dependent phosphodiesterase during ontogenesis of chick retina." in: Journal of neuroscience research, Vol. 86, Issue 5, pp. 1017-23, (2008) (PubMed).

    Murray, Patel, Suda, Zhang, Thistlethwaite, Yuan, Insel: "Expression and activity of cAMP phosphodiesterase isoforms in pulmonary artery smooth muscle cells from patients with pulmonary hypertension: role for PDE1." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 292, Issue 1, pp. L294-303, (2007) (PubMed).

    Dunkern, Hatzelmann: "Characterization of inhibitors of phosphodiesterase 1C on a human cellular system." in: The FEBS journal, Vol. 274, Issue 18, pp. 4812-24, (2007) (PubMed).

    Baxendale, Fraser: "Mammalian sperm phosphodiesterases and their involvement in receptor-mediated cell signaling important for capacitation." in: Molecular reproduction and development, Vol. 71, Issue 4, pp. 495-508, (2006) (PubMed).

    Dolci, Belmonte, Santone, Giorgi, Pellegrini, Carosa, Piccione, Lenzi, Jannini: "Subcellular localization and regulation of type-1C and type-5 phosphodiesterases." in: Biochemical and biophysical research communications, Vol. 341, Issue 3, pp. 837-46, (2006) (PubMed).

    Santone, Giorgi, Maccarone, Basso, Deplano, Bisti: "Gene expression and protein localization of calmodulin-dependent phosphodiesterase in adult rat retina." in: Journal of neuroscience research, Vol. 84, Issue 5, pp. 1020-6, (2006) (PubMed).

  • 抗原
    PDE1C (phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C))
    别名
    PDE1C (PDE1C 产品)
    别名
    CG14940 antibody, CG14942 antibody, CG14943 antibody, CG14944 antibody, CG31757 antibody, CG31758 antibody, CG42325 antibody, CG44007 antibody, Dmel\\CG44007 antibody, Dmel_CG14940 antibody, Dmel_CG14943 antibody, Dmel_CG14944 antibody, Dmel_CG31757 antibody, Dmel_CG31758 antibody, Dmel_CG42325 antibody, PDE1C antibody, PDE1c antibody, GB13690 antibody, Hcam3 antibody, Phosphodiesterase 1c antibody, phosphodiesterase 1C antibody, calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A antibody, calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C antibody, phosphodiesterase 1C, calmodulin-dependent b antibody, Pde1c antibody, PDE1C antibody, LOC724389 antibody, LOC100019026 antibody, pde1cb antibody
    NCBI登录号
    XP_004857
    UniProt
    Q14123
    途径
    EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
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