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LPP 抗体 (AA 1-109)

LPP 适用: 人, 大鼠, Pig WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2745541
发货至: 中国
  • 抗原 See all LPP 抗体
    LPP (Lipoma-preferred partner (LPP))
    抗原表位
    • 15
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-109
    适用
    • 31
    • 29
    • 10
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, Pig
    宿主
    • 42
    • 3
    • 1
    克隆类型
    • 41
    • 5
    多克隆
    标记
    • 21
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LPP antibody is un-conjugated
    应用范围
    • 19
    • 13
    • 13
    • 12
    • 9
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)
    特异性
    Recognizes human, rat and pig LPP.
    交叉反应
    人, 猪, 大鼠
    纯化方法
    Antigen affinity purified.
    组件
    Contains Positive Control: Human skin fibroblast protein, supplied at 1mg/ml in SDS (Laemmli) sample buffer. Use 25μl (25μg) per lane for Western blotting.
    免疫原
    Recombinant human lipoma preferred partner (LPP) (aa 1-109).
    Top Product
    Discover our top product LPP Primary Antibody
  • 应用备注
    Use 25 μL (25 μg) per lane for Western blotting.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    In PBS containing 0.01 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    有效期
    12 months
  • 抗原
    LPP (Lipoma-preferred partner (LPP))
    别名
    Lipoma Preferred Partner (LPP 产品)
    背景
    Lipoma preferred partner (LPP) is encoded by the preferred fusion partner gene of the high mobility group protein HMGI-C. LPP is frequently affected by chromosomal translocations in a major group of soft tissue lipomas, as well as in a parosteal lipoma and in pulmonary chondroid hamartomas. The resulting fusion proteins comprise three DNA binding domains of HMGI-C fused to two or three C-terminal LIM domains of LPP and a reciprocal product, respectively. Expression of a HMGI-C/LPP fusion protein causes malignant transformation of fibroblasts. Similar to its relatives zyxin and TRIP (thyroid receptor interacting protein 6) / ZRP-1 (zyxin-related protein 1), LPP consists of a N-terminal proline-rich domain followed by three C-terminal LIM domains (double zinc finger structures that are involved in protein-protein interactions). Like the cytoskeletal protein zyxin, LPP localizes to focal adhesions and cell-cell adherens junctions. LPP harbors a nuclear export signal and displays transcriptional activation capacity.
    UniProt
    Q93052
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