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BMF 抗体 (AA 13-27, AA 112-126)

This anti-BMF antibody is a 大鼠 单克隆 antibody detecting BMF in WB, IHC, ELISA, IP, FACS 和 ICC. Suitable for 小鼠 和 大鼠.
产品编号 ABIN2745519
发货至: 中国

Quick Overview for BMF 抗体 (AA 13-27, AA 112-126) (ABIN2745519)

抗原

See all BMF 抗体
BMF (Bcl2 Modifying Factor (BMF))

适用

  • 36
  • 15
  • 11
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
小鼠, 大鼠

宿主

  • 31
  • 3
  • 2
大鼠

克隆类型

  • 30
  • 6
单克隆

标记

  • 24
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BMF antibody is un-conjugated

应用范围

  • 28
  • 15
  • 10
  • 7
  • 3
  • 3
  • 3
  • 3
  • 2
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Flow Cytometry (FACS), Immunocytochemistry (ICC)

克隆位点

17A9
  • 抗原表位

    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 13-27, AA 112-126

    特异性

    Recognizes an epitope within the peptide sequence aa 13-27 of mouse and rat Bmf. Detects bands of ~25 kDa and ~30 kDa by Western blot, corresponding to endogenous Bmf and BmfL.

    交叉反应

    小鼠, 大鼠

    无交叉反应

    交叉反应 (详细)

    Does not cross-react with human Bmf.

    纯度

    >95 % (SDS-PAGE)

    内毒素水平

    <0.1EU/μg purified protein (LAL test, Lonza).

    免疫原

    Recombinant full length mouse Bmf and synthetic peptides corresponding to aa 13-27 and aa 112-126 of mouse Bmf.

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    In PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.

    有效期

    12 months
  • 抗原

    BMF (Bcl2 Modifying Factor (BMF))

    别名

    Bmf

    背景

    Bmf (Bcl-2-modifying factor) belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homo-dimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bmf contains a single Bcl-2 homology domain 3 (BH3), and has been shown to interact with other Bcl-2 proteins and functions as an apoptotic activator. Two different start sites can give rise to two proteins of 25 or 30 kDa. It is found to be sequestered to myosin V motors by its association with dynein light chain 2 (DLC2), which may be important for sensing intracellular damage and triggering apoptosis.

    UniProt

    Q91ZE9
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