TDP1 抗体
-
- 抗原 See all TDP1 抗体
- TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This TDP1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 产品特性
- Homo sapiens tyrosyl-DNA phosphodiesterase 1 (TDP1), transcript variant 1
- 纯化方法
- Purified from mouse ascites fluids by affinity chromatography
- 免疫原
- Full length human recombinant protein of human TDP1(NP_060789) produced in HEK293T cell.
- 克隆位点
- 4H1
- 亚型
- IgG1
- Top Product
- Discover our top product TDP1 Primary Antibody
-
-
- 应用备注
- WB 1:2000,
- 说明
-
The concentration of the product may vary between diferrent lots.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.5-1.0 mg/mL
- 缓冲液
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
-
- 抗原
- TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
- 别名
- TDP1 (TDP1 产品)
- 别名
- 2810481F14Rik antibody, 4921509N21Rik antibody, AI838772 antibody, AW493413 antibody, E430034L06Rik antibody, MLZ-501 antibody, SCAN1 antibody, tdp1 antibody, MGC83708 antibody, TDP1 antibody, F8M21.60 antibody, F8M21_60 antibody, tyrosyl-DNA phosphodiesterase 1 antibody, tyrosyl-DNA phosphodiesterase 1 antibody, tyrosyl-DNA Phosphodiesterase (Tdp1) antibody, tyrosyl-DNA phosphodiesterase 1 L homeolog antibody, tyrosyl-DNA phosphodiesterase-like protein antibody, TDP1 antibody, Tc00.1047053511191.10 antibody, Tdp1 antibody, tdp1.L antibody, tdp1 antibody, PTRG_11198 antibody, MCYG_02121 antibody, MGYG_03035 antibody
- 背景
- The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform.
- 分子量
- 68.2 kDa
- 基因ID
- 55775
- NCBI登录号
- NM_018319
- HGNC
- 55775
-