LGR5 抗体 (AA 250-550)
(16 references)-
- 抗原 See all LGR5 抗体
- LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))
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抗原表位
- AA 250-550
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适用
- 人, 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This LGR5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- 产品特性
- Homo sapiens leucine-rich repeat containing G protein-coupled receptor 5 (LGR5)
- 纯化方法
- Purified from mouse ascites fluids by affinity chromatography
- 免疫原
- Human recombinant protein fragment corresponding to amino acids 250-550 of human LGR5 (NP_003658) produced in HEK293T Cell.
- 克隆位点
- 2A2
- 亚型
- IgG1
- Top Product
- Discover our top product LGR5 Primary Antibody
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anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 810-907) antibody
LGR5 适用: 人, 小鼠 WB, FACS, ELISA, IHC (p), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 443-473) antibodyLGR5 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB14555 unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 22-178) antibodyLGR5 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 2B5B9 unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 689-719) antibodyLGR5 适用: 人, 小鼠, 大鼠 WB, FACS 宿主: 兔 Polyclonal RB14211 unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 689-719) antibodyLGR5 适用: 人, 小鼠, 大鼠 WB, FACS, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 443-473) antibodyLGR5 适用: 人 WB, FACS, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (Cytoplasmic Domain) antibodyLGR5 适用: 人 IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 824-907) antibodyLGR5 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 241-352) antibodyLGR5 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) antibodyLGR5 适用: 人 WB, FACS, ELISA 宿主: 兔 Monoclonal 4H8 unconjugated Recombinant Antibody
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- 应用备注
- WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100, IP 2 μg/500 μL
- 说明
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The concentration of the product may vary between diferrent lots.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5-1.0 mg/mL
- 缓冲液
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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: "Heparan sulfate hexasaccharide selectively inhibits cancer stem cells self-renewal by activating p38 MAP kinase." in: Oncotarget, Vol. 7, Issue 51, pp. 84608-84622, (2018) (PubMed).
: "Immuno-proteomic discovery of tumor tissue autoantigens identifies olfactomedin 4, CD11b, and integrin alpha-2 as markers of colorectal cancer with liver metastases." in: Journal of proteomics, Vol. 168, pp. 53-65, (2018) (PubMed).
: "Liver damage, proliferation, and progenitor cell markers in experimental necrotizing enterocolitis." in: Journal of pediatric surgery, Vol. 53, Issue 5, pp. 909-913, (2018) (PubMed).
: "NANOGP8 is the key regulator of stemness, EMT, Wnt pathway, chemoresistance, and other malignant phenotypes in gastric cancer cells." in: PLoS ONE, Vol. 13, Issue 4, pp. e0192436, (2018) (PubMed).
: "Resveratrol reduces senescence-associated secretory phenotype by SIRT1/NF-κB pathway in gut of the annual fish Nothobranchius guentheri." in: Fish & shellfish immunology, Vol. 80, pp. 473-479, (2018) (PubMed).
: "LGR5 Is a Gastric Cancer Stem Cell Marker Associated with Stemness and the EMT Signature Genes NANOG, NANOGP8, PRRX1, TWIST1, and BMI1." in: PLoS ONE, Vol. 11, Issue 12, pp. e0168904, (2017) (PubMed).
: "Full-length LGR5-positive cells have chemoresistant characteristics in colorectal cancer." in: British journal of cancer, Vol. 114, Issue 11, pp. 1251-60, (2016) (PubMed).
: "A recellularized human colon model identifies cancer driver genes." in: Nature biotechnology, Vol. 34, Issue 8, pp. 845-51, (2016) (PubMed).
: "CBB1003, a lysine-specific demethylase 1 inhibitor, suppresses colorectal cancer cells growth through down-regulation of leucine-rich repeat-containing G-protein-coupled receptor 5 expression." in: Journal of cancer research and clinical oncology, Vol. 141, Issue 1, pp. 11-21, (2015) (PubMed).
: "LGR5 Activates Noncanonical Wnt Signaling and Inhibits Aldosterone Production in the Human Adrenal." in: The Journal of clinical endocrinology and metabolism, Vol. 100, Issue 6, pp. E836-44, (2015) (PubMed).
: "Postnatal epithelium and mesenchyme stem/progenitor cells in bioengineered amelogenesis and dentinogenesis." in: Biomaterials, Vol. 35, Issue 7, pp. 2172-80, (2014) (PubMed).
: "Identification of a distinct small cell population from human bone marrow reveals its multipotency in vivo and in vitro." in: PLoS ONE, Vol. 9, Issue 1, pp. e85112, (2014) (PubMed).
: "LGR5 regulates survival through mitochondria-mediated apoptosis and by targeting the Wnt/?-catenin signaling pathway in colorectal cancer cells." in: Cellular signalling, Vol. 26, Issue 11, pp. 2333-42, (2014) (PubMed).
: "Excision of uracil from transcribed DNA negatively affects gene expression." in: The Journal of biological chemistry, Vol. 289, Issue 32, pp. 22008-18, (2014) (PubMed).
: "Lgr5 expression as stem cell marker in human gastric gland and its relatedness with other putative cancer stem cell markers." in: Gene, Vol. 525, Issue 1, pp. 18-25, (2013) (PubMed).
: "PKH26 staining defines distinct subsets of normal human colon epithelial cells at different maturation stages." in: PLoS ONE, Vol. 7, Issue 8, pp. e43379, (2012) (PubMed).
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: "Heparan sulfate hexasaccharide selectively inhibits cancer stem cells self-renewal by activating p38 MAP kinase." in: Oncotarget, Vol. 7, Issue 51, pp. 84608-84622, (2018) (PubMed).
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- 抗原
- LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))
- 别名
- LGR5 (LGR5 产品)
- 别名
- lgr5-a antibody, lgr5a antibody, FEX antibody, Gpr49 antibody, GPR49 antibody, GPR67 antibody, GRP49 antibody, HG38 antibody, leucine-rich repeat containing G protein-coupled receptor 5 L homeolog antibody, leucine rich repeat containing G protein coupled receptor 5 antibody, leucine rich repeat containing G protein-coupled receptor 5 antibody, lgr5.L antibody, Lgr5 antibody, LGR5 antibody
- 背景
- LGR5 (leucine-rich repeat containing G protein-coupled receptor 5) An Orphan GPCR protein, contains large extracellular domain, Stem cell biomarker for small intestine, active in colon cancer, overexpressed in ovary and liver tumors.
- 分子量
- 99.8 kDa
- 基因ID
- 8549
- NCBI登录号
- NM_003667
- HGNC
- 8549
- 途径
- WNT signaling
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