CD44 抗体 (APC)
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- 抗原 See all CD44 抗体
- CD44
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD44 antibody is conjugated to APC
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应用范围
- Flow Cytometry (FACS)
- 特异性
- The antibody MEM-85 reacts with both cell surface-expressed and soluble form of CD44 antigen (Phagocyte glycoprotein 1), a 80-95 kDa transmembrane glycoprotein (hyaladherin family) present on the most of cells and tissues (leukocytes, endothelial cells, mesenchymal cells, etc.), it is negative on platelets and hepatocytes.
- 纯化方法
- Size-Exclusion Chromatography
- 免疫原
- Leukocytes of a patient suffering from LGL Type Leukaemia
- 克隆位点
- MEM-85
- 亚型
- IgG2b
- Top Product
- Discover our top product CD44 Primary Antibody
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- 应用备注
- Further Comments: HLDA IV, WS Code NL 706 HLDA VI, WS Code AS Ref.15
- 限制
- 仅限研究用
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- 缓冲液
- Phosphate buffered saline (PBS) containing 15 mM Sodium Azide and 0.2 % (w/v) high-grade protease free BSA as a stabilizing agent
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
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Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Shelf Life: one year from despatch. - 有效期
- 12 months
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- 抗原
- CD44
- 别名
- CD44 (CD44 产品)
- 背景
- CD44 is a type 1 transmembrane glycoprotein also known as Phagocytic Glycoprotein 1 (pgp 1) and HCAM. CD44 is the receptor for hyaluronate and exists as a large number of different isoforms due to alternative RNA splicing. The major isoform expressed on lymphocytes, myeloid cells, and erythrocytes is a glycosylated type 1 transmembrane protein. Other isoforms contain glycosaminoglycans and are expressed on hematopoietic and non hematopoietic cells. CD44 is involved in adhesion of leukocytes to endothelial cells, stromal cells, and the extracellular matrix.Synonyms: CDw44, ECMR-III, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, LHR, MDU2, MDU3, MIC4, PGP-1, Phagocytic glycoprotein 1
- 基因ID
- 960
- UniProt
- P16070
- 途径
- Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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