ADD3 抗体
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- 抗原 See all ADD3 抗体
- ADD3 (Adducin 3 (Gamma) (ADD3))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ADD3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of Adducin γ protein. (region surrounding Pro452)
- 交叉反应 (详细)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- 纯度
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product ADD3 Primary Antibody
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- 应用备注
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- DO NOT FREEZE!
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- ADD3 (Adducin 3 (Gamma) (ADD3))
- 别名
- gamma-Adducin (ADD3) (ADD3 产品)
- 别名
- gamma-adducin antibody, add3 antibody, MGC89418 antibody, ADD3 antibody, DKFZp459E0630 antibody, ADDL antibody, AI463285 antibody, R75380 antibody, adducin 3 (gamma) antibody, adducin 3 antibody, adducin 3 L homeolog antibody, ADD3 antibody, add3 antibody, add3.L antibody, Add3 antibody
- 背景
- Adducins are a family of cytoskeleton proteins encoded by three genes (α, β and γ). Adducin is a protein associated with the inner leaflet of the plasma membrane and is one of the proteins localized at the spectrin-actin junction of the membrane skeleton. The cortical actin cytoskeletal network is lost during apoptosis and adducins are central in the cortical actin network organization. Adducin α is a cytoskeletal protein involved with sodium-pump activity in the renal tubule and is associated with hypertension. The expression of Adducin α and Adducin γ is ubiquitous in contrast to the restricted expression of Adducin β. Adducin β is expressed at high levels in brain andhematopoietic tissues, such as bone marrow in humans, and spleen in mice.Synonyms: ADDL, Adducin 3, Adducin-like protein 70
- 分子量
- approx. 82 kDa
- 基因ID
- 120
- NCBI登录号
- NP_001112
- UniProt
- Q9UEY8
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