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YWHAE 抗体

YWHAE 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN272265
发货至: 中国
  • 抗原 See all YWHAE 抗体
    YWHAE (14-3-3 epsilon (YWHAE))
    适用
    • 56
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    人, 小鼠, 大鼠
    宿主
    • 53
    • 4
    • 1
    克隆类型
    • 47
    • 11
    多克隆
    标记
    • 27
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    This YWHAE antibody is un-conjugated
    应用范围
    • 41
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    • 13
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    • 9
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    • 5
    • 3
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    • 1
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects endogenous levels of 14-3-3 ε protein. (region surrounding Asp238)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography using epitope-specific immunogen
    Top Product
    Discover our top product YWHAE Primary Antibody
  • 应用备注
    ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8° for one month or (in aliquots) at -20 °C for longer.
  • Hu, Sun, Li, Wang, Cai, Li, Zhao: "In Ovo injection of betaine affects hepatic cholesterol metabolism through epigenetic gene regulation in newly hatched chicks." in: PLoS ONE, Vol. 10, Issue 4, pp. e0122643, (2016) (PubMed).

    Nagappan, Park, Park, Hong, Yumnam, Lee, Kim, Kim, Lee, Lee, Cho, Lee, Won, Cho, Kim: "Helicobacter pylori infection combined with DENA revealed altered expression of p53 and 14-3-3 isoforms in Gulo-/- mice." in: Chemico-biological interactions, Vol. 206, Issue 2, pp. 143-52, (2013) (PubMed).

  • 抗原
    YWHAE (14-3-3 epsilon (YWHAE))
    别名
    14-3-3 Protein epsilon (YWHAE 产品)
    别名
    14-3-3 antibody, 14-3-3 epsilon antibody, 14-3-3-e antibody, 14-3-3-epsilon antibody, 14-3-30epsilon antibody, 14-3-3EPSILON antibody, 14-3-3e antibody, 14-3-3omicron antibody, 1433epsilon antibody, 143E_DROME antibody, CG31196 antibody, CT24092 antibody, D14-3-3e antibody, D14-3-3epsilon antibody, Dmel\\CG31196 antibody, EK3-5 antibody, PAR-5 antibody, PAR5 antibody, Par-5 antibody, SR3-9 antibody, Su(Raf)3B antibody, anon-WO0172774.141 antibody, anon-WO02059370.52 antibody, d14-3-3epsilon antibody, eps antibody, l(3)j2B10 antibody, par-5 antibody, 14-3-3epsilon antibody, kcip-1 antibody, mdcr antibody, mds antibody, LOC581376 antibody, Ywhae antibody, ACYPI002517 antibody, YWHAE antibody, 14-3-3E antibody, KCIP-1 antibody, MDCR antibody, MDS antibody, AU019196 antibody, fe38c12 antibody, wu:fb48f06 antibody, wu:fe38c12 antibody, wu:fi22e10 antibody, ywhae antibody, zgc:55377 antibody, zgc:77062 antibody, CG31196 gene product from transcript CG31196-RD antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon antibody, 14-3-3 epsilon antibody, 14-3-3 epsilon protein antibody, 14-3-3 protein epsilon antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon S homeolog antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1 antibody, 14-3-3epsilon antibody, ywhae antibody, LOC581376 antibody, Ywhae antibody, HCAG_04173 antibody, PTRG_02836 antibody, PTRG_04459 antibody, UREG_07864 antibody, YWHAE antibody, ywhae.S antibody, ywhae1 antibody
    背景
    14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms comprise this family of signaling intermediates, denoted 14-3-3 β, γ, ε, ζ, η, θ and σ. 14-3-3 proteins form dimers that present two binding sites for ligand proteins, thereby bringing together two proteins that may not otherwise associate. These ligands largely share a 14-3-3 consensus binding motif and exhibit serine/threonine phosphorylation. 14-3-3 proteins function in broad regulation of these ligand proteins, by cytoplasmic sequestration, occupation of interaction domains and import/export sequences, prevention of degradation, activation/repression of enzymatic activity and facilitation of protein modification, and thus loss of expression contributes to a vast array of pathogenic cellular activities.Synonyms: 14-3-3E, YWHAE
    分子量
    approx. 29 kDa
    基因ID
    7531
    NCBI登录号
    NP_006752
    UniProt
    P62258
    途径
    Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, M Phase
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