DCP1A 抗体
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- 抗原 See all DCP1A 抗体
- DCP1A (DCP1 Decapping Enzyme Homolog A (S. Cerevisiae) (DCP1A))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DCP1A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of SMIF protein. (region surrounding Ser133)
- 交叉反应 （详细）
- Species reactivity (tested):Human, Mouse.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- 纯度
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product DCP1A Primary Antibody
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anti-DCP1 Decapping Enzyme Homolog A (S. Cerevisiae) (DCP1A) (AA 186-285) antibody
DCP1A 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3G4 unconjugated
anti-DCP1 Decapping Enzyme Homolog A (S. Cerevisiae) (DCP1A) antibodyDCP1A 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-DCP1 Decapping Enzyme Homolog A (S. Cerevisiae) (DCP1A) (AA 303-582) antibodyDCP1A 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-DCP1 Decapping Enzyme Homolog A (S. Cerevisiae) (DCP1A) antibodyDCP1A 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-DCP1 Decapping Enzyme Homolog A (S. Cerevisiae) (DCP1A) (AA 186-285) antibodyDCP1A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D12 unconjugated
anti-DCP1 Decapping Enzyme Homolog A (S. Cerevisiae) (DCP1A) (AA 186-285) antibodyDCP1A 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2F11 unconjugated
anti-DCP1 Decapping Enzyme Homolog A (S. Cerevisiae) (DCP1A) (Internal Region) antibodyDCP1A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-DCP1 Decapping Enzyme Homolog A (S. Cerevisiae) (DCP1A) (AA 186-285) antibodyDCP1A 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-DCP1 Decapping Enzyme Homolog A (S. Cerevisiae) (DCP1A) (AA 1-582) antibodyDCP1A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-DCP1 Decapping Enzyme Homolog A (S. Cerevisiae) (DCP1A) (Internal Region) antibodyDCP1A 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- DO NOT FREEZE!
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- DCP1A (DCP1 Decapping Enzyme Homolog A (S. Cerevisiae) (DCP1A))
- 别名
- DCP1A (DCP1A 产品)
- 别名
- DCP1A antibody, 1110066A22Rik antibody, 4930568L04Rik antibody, AU019772 antibody, D14Ertd817e antibody, Mitc1 antibody, SMIF antibody, RGD1561298 antibody, mitc1 antibody, HSA275986 antibody, Nbla00360 antibody, SMAD4IP1 antibody, smad4ip1 antibody, smif antibody, decapping mRNA 1A antibody, decapping mRNA 1A L homeolog antibody, DCP1A antibody, Dcp1a antibody, dcp1a antibody, dcp1a.L antibody
- 背景
- Signal transduction of TGF-beta superfamily members is regulated by Smad proteins. In particular, Smads influence specific gene transcription by relaying signals from the cell membrane to the nucleus. Smad4 plays an essential role in TGF-beta-induced transcriptional activation wherein phosphorylated receptor-associated Smads associate with Smad4. Furthermore, SMIF (Smad4-intereacting protein) and Smad4 complex with TGF-beta and BMP4. An increase in Smad4 concentration increases the translocation of this complex to the nucleus. SMIF and Smad4 interact directly through a EVH1/WH1 domain on SMIF and a proline-rich activation domain on Smad4. Smad4 is essential to nuclear translocation of SMIF as deletion of the Smad4-interacting domain (located in the N-terminal 100 amino acids) of SMIF eliminates TGF-β-induced nuclear translocation of SMIF (1). The human SMIF gene is ubiquitously expressed and encodes a protein with a relative molecular mass of 70 kDa.Synonyms: SMIF, Smad4-interacting transcriptional co-activator, Transcription factor SMIF, mRNA-decapping enzyme 1A
- 分子量
- approx. 75 kDa
- 基因ID
- 55802
- NCBI登录号
- NP_060873
- UniProt
- Q9NPI6
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