MAPKAP Kinase 3 抗体
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- 抗原 See all MAPKAP Kinase 3 (MAPKAPK3) 抗体
- MAPKAP Kinase 3 (MAPKAPK3) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MAPKAP Kinase 3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of 3pK protein. (region surrounding Arg319)
- 交叉反应 (详细)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- 纯度
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product MAPKAPK3 Primary Antibody
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- 应用备注
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ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- DO NOT FREEZE!
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- MAPKAP Kinase 3 (MAPKAPK3) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 3 (MAPKAPK3))
- 别名
- MAPKAP Kinase-3 (MAPKAPK3 产品)
- 别名
- 3PK antibody, MAPKAP-K3 antibody, MAPKAP3 antibody, MAPKAPK-3 antibody, MK-3 antibody, AI874665 antibody, MK3 antibody, MapkKapk3 antibody, MAPKAPK3 antibody, mapkapk3 antibody, MGC154360 antibody, 3pk antibody, mapkap3 antibody, zgc:158342 antibody, mitogen-activated protein kinase-activated protein kinase 3 antibody, mitogen-activated protein kinase-activated protein kinase 3 S homeolog antibody, MAPKAPK3 antibody, Mapkapk3 antibody, mapkapk3.S antibody, mapkapk3 antibody
- 背景
- The MAPKAP kinases (for MAP kinase activated protein kinases) are a group of MAP kinase substrates which are themselves kinases. In response to activation, the MAP kinases phosphorylate downstream components on a consensus Pro-X-Ser/Thr-Pro motif. Several kinases that contain this motif have been identifed and serve as substrates for the ERK and p38 MAP kinases. These include the serine/threonine kinases Rsk-1 (also designated MAPKAP kinase-1), Rsk-2 and Rsk-3, which are phosphorylated by ERK 1 and ERK 2. Similarly, p38 phosphorylates and activates the serine/threonine kinases MAPKAPK-2 and MAPKAPK-3 (also designated 3pK). The serine/threonine kinases Mnk1 and Mnk2 are substrates for both ERK and p38 MAP kinases.Synonyms: MAP kinase-activated protein kinase 3, MAPK-activated protein kinase 3, MAPKAPK-3, MAPKAPK3
- 分子量
- approx. 42 kDa
- 基因ID
- 7867
- NCBI登录号
- NP_004626
- UniProt
- Q16644
- 途径
- MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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