SYT1 抗体
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- 抗原 See all SYT1 抗体
- SYT1 (Synaptotagmin I (SYT1))
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SYT1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of SYT protein. (region surrounding Ala7)
- 交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- 纯度
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product SYT1 Primary Antibody
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anti-Synaptotagmin I (SYT1) (AA 1-422) antibody
SYT1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) (AA 136-422) antibodySYT1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) antibodySYT1 适用: 人, 大鼠, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) (AA 1-422) antibodySYT1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A5 unconjugated
anti-Synaptotagmin I (SYT1) (pSer309) antibodySYT1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) antibodySYT1 适用: 人, 大鼠, 小鼠 WB, IHC, ICC, IHC (fro), FACS 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) antibodySYT1 适用: 人, 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) (AA 1-422) antibodySYT1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1A6 unconjugated
anti-Synaptotagmin I (SYT1) (AA 301-523) antibodySYT1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Synaptotagmin I (SYT1) (pThr202) antibodySYT1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1: 1000approx. 1: 5000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1,0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- DO NOT FREEZE!
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- SYT1 (Synaptotagmin I (SYT1))
- 别名
- Synaptotagmin-1 (SYT1 产品)
- 背景
- The transcriptional coactivator SYT (synovial translocation protein) contains a conserved amino terminal SNH domain and a carboxy terminal QPGY domain, which is a functioning transcriptional activating sequence. Synovial sarcoma translocation (SSX) proteins, including SSX1-5, are transcriptional repressors that contain a repressor domain in their carboxy termini. SSX proteins are localized to the nucleus and expressed in testis and several types of cancers and, therefore, they are classified as C/T (cancer/testis) antigens. The t(x,18) translocation results in the fusion of the amino terminus of SYT to the carboxy terminus of either SSX1 or SSX2, both fusions result in the production of transcriptional activators. SYT-SSX chimeras are detected in most synovial sarcomas. Synovial sarcomas are responsible for up to 10 % of soft issue sarcomas and are histologically characterized as either biphasic or monophasic.Genetic analysis indicates that biphasic synovial sarcomas contain SYT-SSX1 fusions, whereas SYT-SSX2 fusions are found in monophasic synovial sarcomas, providing additional distinguishing characterization of these subtypes.Synonyms: SVP65, SYT, SYT1, Synaptotagmin I, Synaptotagmin1, SytI, p65
- 分子量
- approx. 45 kDa
- 基因ID
- 6857
- NCBI登录号
- NP_001129277
- UniProt
- P21579
- 途径
- Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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