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p53 抗体
GMP Grade
TP53
适用: 人
WB
宿主: 小鼠
Monoclonal
PAB122
unconjugated
p53抗体详情
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抗原
See all p53 (TP53) 抗体
p53 (TP53)
(Tumor Protein P53 (TP53))
适用
All reactivities for p53 抗体
人
宿主
All hosts for p53 抗体
小鼠
克隆类型
All clonalities for p53 抗体
单克隆
标记
All conjugates for p53 抗体
This p53 antibody is un-conjugated
应用范围
All applications for p53 抗体
Western Blotting (WB)
原理
Anti-p53 Unconjugated Antibody
产品特性
p53, a DNA-binding, oligomerization domain- and transcription activation domaincontaining tumor suppressor, upregulates growth arrest and apoptosis-related genes in response to stress signals, thereby influencing programmed cell death, cell differentiation, and cell cycle control mechanisms. p53 localizes in the nucleus, yet can be chaperoned to the cytoplasm by the negative regulator, MDM2. p53 fluctuates between latent and active DNA-binding conformations and is differentially activated through post-translational modifications, including phosphorylation and acetylation.
纯化方法
Purified
纯度
>95 %
质量等级
GMP Grade
免疫原
SV40-transformed, 3T3 clone 4 mouse cells
克隆位点
PAB122
亚型
IgG2b, kappa
Top Product
Discover our top product TP53 Primary Antibody
Alternatives
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anti-Tumor Protein P53 (TP53) (AA 301-393) antibody
TP53
适用: 人, 小鼠, 大鼠, 山羊
WB, ELISA, FACS, IHC (p), ICC, IF (cc), IF (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
0.5 mg/mL
缓冲液
PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C
p53目标详情
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抗原
p53 (TP53)
(Tumor Protein P53 (TP53))
别名
p53 (TP53 产品 )
别名
BCC7 antibody, LFS1 antibody, P53 antibody, TRP53 antibody, p53 antibody, Trp53 antibody, brp53 antibody, drp53 antibody, etID22686.5 antibody, fb40d06 antibody, wu:fb40d06 antibody, zgc:111919 antibody, Tp53 antibody, bbl antibody, bfy antibody, bhy antibody, p44 antibody, tp53 antibody, Xp53 antibody, TP53 antibody, tumor protein p53 antibody, cellular tumor antigen p53 antibody, transformation related protein 53 antibody, tumor protein p53 L homeolog antibody, TP53 antibody, CpipJ_CPIJ002758 antibody, Tp53 antibody, tp53 antibody, Trp53 antibody, tp53.L antibody
NCBI登录号
NM_000546
UniProt
P04637
途径
p53 Pathway , MAPK Pathway , PI3K-Akt Signaling , Apoptosis , AMPK Signaling , Chromatin Binding , ER-Nucleus Signaling , Positive Regulation of Endopeptidase Activity , Hepatitis C , Protein targeting to Nucleus , Autophagy , Warburg Effect
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