(3 references)-
- 抗原 See all Qa-2 products
- Qa-2
- 适用
- 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Qa-2 antibody is conjugated to Biotin
- 应用范围
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 品牌
- BD Pharmingen™
- 产品特性
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The 1-1-2 antibody reacts with the Qa-2 MHC class Ib antigen, which is expressed at higher levels on mature T lymphocytes than on B cells. Its expression is upregulated in the late stages of T-cell maturation. Qa-2 is a 40 kDa GPI-linked cell surface molecule encoded by the Q5, Q6, Q7, and/or Q9 genes of the H-2 complex. A 39 kDa soluble form results from alternative splicing of the transcript. Although Qa-2 is nonpolymorphic, its level of expression on both T and B lymphocytes varies among inbred mouse strains. High expressors include strains carrying the H-2[b] haplotype low expressors include H-2[d] strains, and H-2[k] strains are Qa-2-negative.
BD Pharmingen™ Biotin Mouse Anti-Mouse Qa-2 - Biotin - Clone 1-1-2 - Isotype Mouse IgG2a, κ - Reactivity Ms - 0.1 mg - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- C3H.SW mouse skin graft and splenocytes
- 克隆位点
- 1-1
- 亚型
- IgG2a kappa
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anti-Qa-2 antibody (PE)
适用: 小鼠 FACS 宿主: 小鼠 Monoclonal 695H1-9-9 PE
anti-Qa-2 antibody适用: 小鼠 FACS 宿主: 小鼠 Monoclonal 695H1-9-9 unconjugated
anti-Qa-2 antibody (FITC)适用: 小鼠 FACS 宿主: 小鼠 Monoclonal 695H1-9-9 FITC
anti-Qa-2 antibody (Biotin)适用: 小鼠 FACS 宿主: 小鼠 Monoclonal 695H1-9-9 Biotin
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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: "Recent thymic emigrants are distinct from most medullary thymocytes." in: European journal of immunology, Vol. 27, Issue 8, pp. 2010-5, (1997) (PubMed).
: "Antigen presentation by major histocompatibility complex class I-B molecules." in: Annual review of immunology, Vol. 12, pp. 839-80, (1994) (PubMed).
: "Epitope clusters of Qa-2 antigens defined by a panel of new monoclonal antibodies." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 142, Issue 10, pp. 3495-502, (1989) (PubMed).
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: "Recent thymic emigrants are distinct from most medullary thymocytes." in: European journal of immunology, Vol. 27, Issue 8, pp. 2010-5, (1997) (PubMed).
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- 抗原
- Qa-2
- Abstract
- Qa-2 产品
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