(6 references)-
- 抗原 See all LY6D 抗体
- LY6D (Lymphocyte Antigen 6 Complex, Locus D (LY6D))
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This LY6D antibody is un-conjugated
- 应用范围
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Cytotoxicity Test (CyTox)
- 品牌
- BD Pharmingen™
- 产品特性
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The 49-H4 antibody reacts with the ThB antigen (Ly-6D), which is a 15- kDa GPI-anchored protein of the Ly-6 multigene family. ThB has been detected on cortical thymocytes, small sIg- Thy-1- and sIg+ lymphoid cells in the bone marrow, thymic medullary epithelial cells, all epidermal layers (except the stratum corneum), and on peripheral B lymphocytes, but not on peripheral T lymphocytes. It has been noted that there is strain-to-strain variation in the expression of the ThB antigen on splenic B cells, those of strains with the Ly-6.2 haplotype (e.g., AKR, C57BL, DBA/2, SJL, SWR) stain more intensely with anti- ThB reagents than those of Ly-6.1 strains (e.g., A, BALB/c, CBA, C3H/He, NZB), and B cells of hybrids of Ly-6.1 and Ly-6.2 strains stain with intermediate intensity. The proportions of the ThB+ B cells and thymocytes do not differ significantly among strains.
BD Pharmingen™ Purified Rat Anti-Mouse Ly-6D - Purified - Clone 49-H4 - Isotype Rat IgG2c, κ - Reactivity Ms - 0.1 mg - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- BALB/c mouse plasmacytoma MOPC-104E
- 克隆位点
- 49
- 亚型
- IgG2c kappa
- Top Product
- Discover our top product LY6D Primary Antibody
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anti-Lymphocyte Antigen 6 Complex, Locus D (LY6D) (AA 21-128) antibody
LY6D 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Lymphocyte Antigen 6 Complex, Locus D (LY6D) (AA 1-128) antibodyLY6D 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C.
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: "Polymorphism at the mouse Thb locus." in: Immunogenetics, Vol. 39, Issue 6, pp. 390-4, (1994) (PubMed).
: "The thymic microenvironment." in: Immunology today, Vol. 14, Issue 9, pp. 445-59, (1993) (PubMed).
: "Isolation and characterization of cDNA clones for the mouse thymocyte B cell antigen (ThB)." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 149, Issue 8, pp. 2615-8, (1992) (PubMed).
: "The phenotypic heterogeneity of mouse thymic stromal cells." in: Immunology, Vol. 70, Issue 1, pp. 66-74, (1990) (PubMed).
: "Molecular weight determination of two genetically linked cell surface murine antigens: ThB and Ly-6." in: Immunogenetics, Vol. 15, Issue 6, pp. 591-9, (1982) (PubMed).
: "Monoclonal antibodies to ThB detect close linkage of Ly-6 and a gene regulating ThB expression." in: Immunogenetics, Vol. 11, Issue 3, pp. 275-91, (1981) (PubMed).
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: "Polymorphism at the mouse Thb locus." in: Immunogenetics, Vol. 39, Issue 6, pp. 390-4, (1994) (PubMed).
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- 抗原
- LY6D (Lymphocyte Antigen 6 Complex, Locus D (LY6D))
- 别名
- Ly-6D (LY6D 产品)
- 别名
- E48 antibody, Ly-6D antibody, Ly-61 antibody, Ly61 antibody, Thb antibody, lymphocyte antigen 6 family member D antibody, lymphocyte antigen 6 complex, locus D antibody, LY6D antibody, Ly6d antibody
- 背景
- Synonyms: ThB
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