(5 references)-
- 抗原 See all Chondroitin Sulfate (CS) 抗体
- Chondroitin Sulfate (CS)
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Chondroitin Sulfate antibody is un-conjugated
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应用范围
- Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS)
- 品牌
- BD Pharmingen™
- 产品特性
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The 9.2.27 monoclonal antibody specifically binds to CSPG4 (chondroitin sulfate proteoglycan 4). CSPG4 is also known as MCSP (melanoma chondroitin sulfate proteoglycan) and NG2 (neural/glial antigen 2). The hybridoma secreting the 9.2.27 antibody was generated using a human melanoma cell extract as the immunogen. Tumor cells display a variety of antigens which have been defined by antibodies. Antibodies that specifically react with tumor-associated antigens are useful in understanding the biology of particular tumor types. Proteoglycans including chondroitin sulfate, keratan sulfate, dermatan sulfate and heparan sulfate are major components of the extracellular matrices of many animal cell types.
BD Pharmingen™ Purified Mouse Anti-Chondroitin Sulfate - Purified - Clone 9.2.27 - Isotype Mouse IgG2a - Reactivity Hu - 0.1 mg - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Extracts of Human M21 Melanoma Cells
- 克隆位点
- 9-2-27
- 亚型
- IgG2a
- Top Product
- Discover our top product CS Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C.
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: "Long-term growth suppression of human glioma xenografts by chemoimmunoconjugates of 4-desacetylvinblastine-3-carboxyhydrazide and monoclonal antibody 9.2.27." in: Cancer research, Vol. 52, Issue 14, pp. 3838-44, (1992) (PubMed).
: "Disialoganglioside GD3 on human melanoma serves as a relevant target antigen for monoclonal antibody-mediated tumor cytolysis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 82, Issue 15, pp. 5155-9, (1985) (PubMed).
: "Biosynthetic studies of proteoglycans in human melanoma cells with a monoclonal antibody to a core glycoprotein of chondroitin sulfate proteoglycans." in: The Journal of biological chemistry, Vol. 259, Issue 20, pp. 12733-41, (1984) (PubMed).
: "Production and characterization of monoclonal antibody to a melanoma specific glycoprotein." in: Hybridoma, Vol. 1, Issue 1, pp. 27-36, (1984) (PubMed).
: "Unique glycoprotein-proteoglycan complex defined by monoclonal antibody on human melanoma cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 79, Issue 4, pp. 1245-9, (1982) (PubMed).
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: "Long-term growth suppression of human glioma xenografts by chemoimmunoconjugates of 4-desacetylvinblastine-3-carboxyhydrazide and monoclonal antibody 9.2.27." in: Cancer research, Vol. 52, Issue 14, pp. 3838-44, (1992) (PubMed).
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- 抗原
- Chondroitin Sulfate (CS)
- 别名
- Chondroitin Sulfate (CS 产品)
- 背景
- Synonyms: CSPG4, NG2, Chondroitin sulfate proteoglycan 4, MCSP, MCSPG, MELCSPG, MSK16
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