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- 抗原 See all IL-10RA (IL10RA) 抗体
- IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
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适用
- 人
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This IL-10RA antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 品牌
- BD Pharmingen™
- 产品特性
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Reacts with 90-110 kDa protein expressed on T cells, B cells, NK cells, and monocyte/macrophages. It belongs to the class II cytokine receptor family which includes IFNγR (CDw119), IFNα/βR (CD118) and tissue factor (CD142). IL-10R has been found to play a role in signal transduction by activating specific STAT proteins (STAT3 and STAT1) and inducing gene transcription. Other reports indicate that IL-10 protein binding to NK cells appears to be stimulatory, in contrast to its binding to T cells and monocytes/macrophages.
BD Pharmingen™ Purified Rat Anti-Human CDw210 - Purified - Clone 3F9 - Isotype Rat IgG2a, κ - Reactivity Hu - 0.1 mg - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 克隆位点
- 3F9
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product IL10RA Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C.
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The EBV IL-10 homologue is a selective agonist with impaired binding to the IL-10 receptor." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 158, Issue 2, pp. 604-13, (1997) (PubMed).
: "The functional characterization of interleukin-10 receptor expression on human natural killer cells." in: Blood, Vol. 85, Issue 12, pp. 3577-85, (1995) (PubMed).
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The EBV IL-10 homologue is a selective agonist with impaired binding to the IL-10 receptor." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 158, Issue 2, pp. 604-13, (1997) (PubMed).
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- 抗原
- IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
- 别名
- CDw210 (IL10RA 产品)
- 别名
- IL10R1 antibody, IL10RA antibody, CD210 antibody, CD210a antibody, CDW210A antibody, HIL-10R antibody, IL-10R1 antibody, IL10R antibody, AW553859 antibody, CDw210 antibody, CDw210a antibody, Il10r antibody, mIL-10R antibody, interleukin 10 receptor subunit alpha antibody, interleukin 10 receptor, alpha antibody, IL10RA antibody, Il10ra antibody
- 背景
- Synonyms: IL-10 receptor
- 途径
- Growth Factor Binding
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