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CD44 Standard 抗体

CD44s 适用: 大鼠 FACS, IHC (f), IP, IHC (fro), IHC (zinc) 宿主: 小鼠 Monoclonal OX unconjugated
产品编号 ABIN2689266
发货至: 中国
  • 抗原 See all CD44 Standard (CD44s) 抗体
    CD44 Standard (CD44s)
    适用
    • 31
    • 12
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    • 6
    大鼠
    宿主
    • 36
    • 1
    小鼠
    克隆类型
    • 37
    单克隆
    标记
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
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    • 3
    • 1
    • 1
    • 1
    • 1
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    This CD44 Standard antibody is un-conjugated
    应用范围
    • 37
    • 31
    • 30
    • 10
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Zinc-fixed Sections) (IHC (zinc))
    品牌
    BD Pharmingen™
    产品特性
    The OX-49 antibody reacts with the glycoprotein CD44H (also known as CD44s) expressed on most leukocytes, except for a subset of B lymphocytes, and at greatly increased levels on T- and B-cell blasts. The epitope recognized by OX-49 antibody has been mapped to a region on both the standard, CD44s, and the splice variant, CD44v, isoforms of CD44. However, recent reports indicate that OX-49 antibody cannot detect the CD44v isoform, possibly due to conformational changes in the epitope. CD44 is a cell adhesion receptor, and its ligand, hyaluronate, is a common component of extracellular matrices.

    BD Pharmingen™ Purified Mouse Anti-Rat CD44H - Purified - Clone OX-49 - Isotype Mouse IgG2a, κ - Reactivity Rat - 0.5 mg
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    Rat T blasts from mixed lymphocyte reactions
    克隆位点
    OX
    亚型
    IgG2a kappa
    Top Product
    Discover our top product CD44s Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C.
  • Noonan, Stevens, Tammi, Tammi, Hernandez, Midura: "Spatial distribution of CD44 and hyaluronan in the proximal tibia of the growing rat." in: Journal of orthopaedic research : official publication of the Orthopaedic Research Society, Vol. 14, Issue 4, pp. 573-81, (1996) (PubMed).

    Stevens, Noonan, Bosch, Rapp, Martin, Kurriger, Maynard, Daniels, Solursh, Tammi, Tammi, Midura: "CD44 in growing normal and neoplastic rat cartilage." in: Annals of the New York Academy of Sciences, Vol. 785, pp. 333-6, (1996) (PubMed).

    Zheng, Katoh, He, Oritani, Miyake, Lesley, Hyman, Hamik, Parkhouse, Farr, Kincade: "Monoclonal antibodies to CD44 and their influence on hyaluronan recognition." in: The Journal of cell biology, Vol. 130, Issue 2, pp. 485-95, (1995) (PubMed).

    Westermann, Nagahori, Walter, Heerwagen, Miyasaka, Pabst et al.: "B and T lymphocyte subsets enter peripheral lymph nodes and Peyer's patches without preference in vivo: no correlation occurs between their localization in different types of high endothelial venules ..." in: European journal of immunology, Vol. 24, Issue 10, pp. 2312-6, (1994) (PubMed).

    Lesley, Hyman, Kincade: "CD44 and its interaction with extracellular matrix." in: Advances in immunology, Vol. 54, Issue 4, pp. 271-335, (1993) (PubMed).

    Arch, Wirth, Hofmann, Ponta, Matzku, Herrlich, Zöller: "Participation in normal immune responses of a metastasis-inducing splice variant of CD44." in: Science (New York, N.Y.), Vol. 257, Issue 5070, pp. 682-5, (1992) (PubMed).

    Paterson, Jefferies, Green, Brandon, Corthesy, Puklavec, Williams: "Antigens of activated rat T lymphocytes including a molecule of 50,000 Mr detected only on CD4 positive T blasts." in: Molecular immunology, Vol. 24, Issue 12, pp. 1281-90, (1988) (PubMed).

  • 抗原
    CD44 Standard (CD44s)
    别名
    CD44H (CD44s 产品)
    背景
    Synonyms: Pgp-1, H-CAM, CD44s
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