CD44 Standard 抗体
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- 抗原 See all CD44 Standard (CD44s) 抗体
- CD44 Standard (CD44s)
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适用
- 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD44 Standard antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Zinc-fixed Sections) (IHC (zinc))
- 品牌
- BD Pharmingen™
- 产品特性
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The OX-49 antibody reacts with the glycoprotein CD44H (also known as CD44s) expressed on most leukocytes, except for a subset of B lymphocytes, and at greatly increased levels on T- and B-cell blasts. The epitope recognized by OX-49 antibody has been mapped to a region on both the standard, CD44s, and the splice variant, CD44v, isoforms of CD44. However, recent reports indicate that OX-49 antibody cannot detect the CD44v isoform, possibly due to conformational changes in the epitope. CD44 is a cell adhesion receptor, and its ligand, hyaluronate, is a common component of extracellular matrices.
BD Pharmingen™ Purified Mouse Anti-Rat CD44H - Purified - Clone OX-49 - Isotype Mouse IgG2a, κ - Reactivity Rat - 0.5 mg - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Rat T blasts from mixed lymphocyte reactions
- 克隆位点
- OX
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product CD44s Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C.
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Spatial distribution of CD44 and hyaluronan in the proximal tibia of the growing rat." in: Journal of orthopaedic research : official publication of the Orthopaedic Research Society, Vol. 14, Issue 4, pp. 573-81, (1996) (PubMed).
: "CD44 in growing normal and neoplastic rat cartilage." in: Annals of the New York Academy of Sciences, Vol. 785, pp. 333-6, (1996) (PubMed).
: "Monoclonal antibodies to CD44 and their influence on hyaluronan recognition." in: The Journal of cell biology, Vol. 130, Issue 2, pp. 485-95, (1995) (PubMed).
: "B and T lymphocyte subsets enter peripheral lymph nodes and Peyer's patches without preference in vivo: no correlation occurs between their localization in different types of high endothelial venules ..." in: European journal of immunology, Vol. 24, Issue 10, pp. 2312-6, (1994) (PubMed).
: "CD44 and its interaction with extracellular matrix." in: Advances in immunology, Vol. 54, Issue 4, pp. 271-335, (1993) (PubMed).
: "Participation in normal immune responses of a metastasis-inducing splice variant of CD44." in: Science (New York, N.Y.), Vol. 257, Issue 5070, pp. 682-5, (1992) (PubMed).
: "Antigens of activated rat T lymphocytes including a molecule of 50,000 Mr detected only on CD4 positive T blasts." in: Molecular immunology, Vol. 24, Issue 12, pp. 1281-90, (1988) (PubMed).
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Spatial distribution of CD44 and hyaluronan in the proximal tibia of the growing rat." in: Journal of orthopaedic research : official publication of the Orthopaedic Research Society, Vol. 14, Issue 4, pp. 573-81, (1996) (PubMed).
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- 抗原
- CD44 Standard (CD44s)
- 别名
- CD44H (CD44s 产品)
- 背景
- Synonyms: Pgp-1, H-CAM, CD44s
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