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- 抗原 See all CD4 抗体
- CD4
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适用
- 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD4 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 品牌
- BD Pharmingen™
- 产品特性
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The OX-35 clone has been reported to react with the CD4 antigen on most thymocytes, a subpopulation of mature T lymphocytes (i.e. MHC class II-restricted T cells, including most T helper cells), monocytes, macrophages, some dendritic cells, and microglia. CD4 is an antigen coreceptor on the T-cell surface that interacts with MHC class II molecules on antigen-presenting cells. It participates in T-cell activation through it's association with the T-cell receptor complex and protein tyrosine kinase Lck. The OX-35 clone has been reported to bind to a different epitope of CD4 than that recognized by the W3/25 and OX-38 clones. Immunohistochemical staining of CD4+ T lymphocytes. Frozen sections of normal rat spleen were stained with the anti-rat CD4 clone OX-35 antibody. CD4+ T lymphocytes in the periarteriolar sheath are identified by the brown staining.
BD Pharmingen™ Purified Mouse Anti-Rat CD4 - Purified - Clone OX-35 - Isotype Mouse IgG2a, κ - Reactivity Rat - 1 mL - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Rat T-cell blasts
- 克隆位点
- OX
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product CD4 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 62.5 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, goat serum, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C.
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Partial restoration of hair growth in the DEBR model for Alopecia areata after in vivo depletion of CD4+ T cells." in: The British journal of dermatology, Vol. 140, Issue 3, pp. 432-7, (2000) (PubMed).
: "Effects of anti-CD4 antibody: enhancement of lymph node PPD-memory T cell response." in: Cellular immunology, Vol. 163, Issue 1, pp. 106-12, (1995) (PubMed).
: "Cell-surface marker analysis of rat thymic dendritic cells." in: Immunology, Vol. 79, Issue 2, pp. 298-304, (1993) (PubMed).
: "The T cell receptor as a multicomponent signalling machine: CD4/CD8 coreceptors and CD45 in T cell activation." in: Annual review of immunology, Vol. 10, pp. 645-74, (1992) (PubMed).
: "The biologic roles of CD2, CD4, and CD8 in T-cell activation." in: Annual review of immunology, Vol. 7, pp. 579-99, (1989) (PubMed).
: "Authentic T helper CD4 (W3/25) antigen on rat peritoneal macrophages." in: The Journal of experimental medicine, Vol. 162, Issue 1, pp. 117-27, (1985) (PubMed).
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Partial restoration of hair growth in the DEBR model for Alopecia areata after in vivo depletion of CD4+ T cells." in: The British journal of dermatology, Vol. 140, Issue 3, pp. 432-7, (2000) (PubMed).
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- 抗原
- CD4
- 别名
- CD4 (CD4 产品)
- 别名
- cd4 antibody, L3T4 antibody, Ly-4 antibody, CD4mut antibody, W3/25 antibody, p55 antibody, CD4 molecule antibody, carcinoembryonic antigen-related cell adhesion molecule 5 antibody, T-cell surface glycoprotein CD4 antibody, CD4 antigen antibody, Cd4 molecule antibody, CD4 antibody, LOC100125525 antibody, cd4 antibody, Cd4 antibody
- 背景
- Synonyms: Cd4, CD4 antigen, p55, W3/25 antigen, T-cell surface glycoprotein CD4
- 途径
- TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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