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- 抗原 See all CD25 (IL2RA) 抗体
- CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
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适用
- 兔
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD25 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunoprecipitation (IP), Blocking Reagent (BR)
- 品牌
- BD Pharmingen™
- 产品特性
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The Kei-α1 antibody reacts with the rabbit homolog of CD25, the interleukin-2 receptor alpha chain (IL-2Rα). mAb Kei-α1 recognizes specifically IL-2Rα and neither the IL-2R ß chain (CD122) nor the 25- kDa protein component of the rabbit high-affinity IL-2R complex. Based on flow cytometric analysis, fewer than 1 % of resting peripheral blood T and B cells have been found to stain with Kei-α1, while a majority of PHA blasts show intense staining with Kei-α1. The HTLV-1-transformed rabbit cell lines, F648b and YR-1 both also show intense staining with Kei-α1. mAb Kei-α1 has been reported to block both high-and low-affinity IL-2 binding and also cell proliferation of rabbit PHA blasts induced by picomolar concentrations of IL-2.
BD Pharmingen™ Purified Mouse Anti-Rabbit CD25 - Purified - Clone Kei-α1 - Isotype Mouse IgG2b, κ - Reactivity Rab - 0.1 mg - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Membrane preparation of the HTLV-1-transformed rabbit T-cell line F648b
- 克隆位点
- Kei
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product IL2RA Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 4°C.
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Generation of monoclonal antibodies to the rabbit interleukin-2 receptor alpha chain (CD25) and its distribution in HTLV-1-transformed rabbit T cells." in: Japanese journal of cancer research : Gann, Vol. 84, Issue 7, pp. 770-5, (1993) (PubMed).
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Generation of monoclonal antibodies to the rabbit interleukin-2 receptor alpha chain (CD25) and its distribution in HTLV-1-transformed rabbit T cells." in: Japanese journal of cancer research : Gann, Vol. 84, Issue 7, pp. 770-5, (1993) (PubMed).
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- 抗原
- CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
- 别名
- CD25 (IL2RA 产品)
- 别名
- CD25 antibody, IDDM10 antibody, IL2R antibody, TCGFR antibody, IL2RAC antibody, IL-2RA antibody, Il2r antibody, Ly-43 antibody, interleukin 2 receptor subunit alpha antibody, interleukin-2 receptor subunit alpha-like antibody, interleukin 2 receptor, alpha chain antibody, IL2RA antibody, Il2ra antibody, LOC100222957 antibody
- 背景
- Synonyms: IL-2R alpha
- 途径
- JAK/STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation
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