MUC1 抗体
(6 references)Quick Overview for MUC1 抗体 (ABIN2689099)
抗原
See all MUC1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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品牌
- BD Pharmingen™
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产品特性
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Reacts with the core peptide of the MUC1 protein, a member of a family of mucin glycoproteins that are characterized by high carbohydrate content, O-linked oligosaccharides, high molecular weight (>200 kDa) and an amino acid composition rich in serine, threonin, proline and glycine. The core protein contains a domain of 20 amino-acid tandem repeats which function as multiple epitopes for the monoclonal antibody. Incomplete glycosylation of some tumor-associated mucins may lead to variable unmasking of the multiple peptide epitopes leading to the observed differences in staining intensity between normal and malignant tissues. This antibody has been shown to react with both normal and malignant epithelia of various tissues including breast and colon. Profile of U266 cells analyzed by flow cytometry
BD Pharmingen™ Purified Mouse Anti-Human CD227 - Purified - Clone HMPV - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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亚型
- IgG1 kappa
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anti-Mucin 1 (MUC1) (AA 474-630) antibody
MUC1 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mucin 1 (MUC1) (AA 410-525) antibodyMUC1 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mucin 1 (MUC1) antibodyMUC1 适用: 人, 小鼠 IHC, WB, ELISA, FACS, IF, Coat, StM 宿主: 小鼠 Monoclonal MUC1-955 unconjugated
anti-Mucin 1 (MUC1) antibodyMUC1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal MUC1-520 unconjugated
anti-Mucin 1 (MUC1) antibodyMUC1 适用: 人 IHC, WB, IHC (p) 宿主: 小鼠 Monoclonal 2E3 unconjugated
anti-Mucin 1 (MUC1) (AA 1182-1255) antibodyMUC1 适用: 人 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Mucin 1 (MUC1) (AA 66-175) antibodyMUC1 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 3B10B4 unconjugated
anti-Mucin 1 (MUC1) (AA 1098-1255) antibodyMUC1 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mucin 1 (MUC1) (AA 404-655) antibodyMUC1 适用: 大鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mucin 1 (MUC1) (AA 1062-1139) antibodyMUC1 适用: 人, 小鼠, 大鼠 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store undiluted at 4°C.
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: "Muc-1 core protein is expressed on multiple myeloma cells and is induced by dexamethasone." in: Blood, Vol. 93, Issue 4, pp. 1287-98, (1999) (PubMed).
: "Detection of circulating anti-MUC1 mucin core protein antibodies in patients with colorectal cancer." in: Journal of gastroenterology, Vol. 33, Issue 3, pp. 354-61, (1998) (PubMed).
: "Anti-MUC1 class I restricted CTLs in metastatic breast cancer patients immunized with a synthetic MUC1 peptide." in: International journal of cancer. Journal international du cancer, Vol. 76, Issue 6, pp. 817-23, (1998) (PubMed).
: "RAG1 and RAG2 form a stable postcleavage synaptic complex with DNA containing signal ends in V(D)J recombination." in: Cell, Vol. 89, Issue 1, pp. 43-53, (1997) (PubMed).
: "Expression of MUC1 and MUC2 mucins by human tumor cell lines." in: Tumour biology, Vol. 13, Issue 5-6, pp. 268-77, (1993) (PubMed).
: "Second-generation monoclonal antibodies to intestinal MUC2 peptide reactive with colon cancer." in: Journal of the National Cancer Institute, Vol. 84, Issue 9, pp. 699-703, (1992) (PubMed).
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: "Muc-1 core protein is expressed on multiple myeloma cells and is induced by dexamethasone." in: Blood, Vol. 93, Issue 4, pp. 1287-98, (1999) (PubMed).
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- MUC1 (Mucin 1 (MUC1))
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别名
- CD227
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背景
- Synonyms: MUC1
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途径
- Negative Regulation of intrinsic apoptotic Signaling
抗原
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