Prelamin A (C-Term), (cleaved), (farnesylated) 抗体
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- 抗原
- Prelamin A
- 抗原表位
- C-Term, cleaved, farnesylated
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- Immunofluorescence (IF)
- 特异性
- Anti cleaved farnesylated prelamin A polyclonal antibody detects carboxymethylated prelamin A harbouring the farnesyl residue. This antibody also recognizes progerin, the truncated form of prelamin A found in HutchinsonGilford Progeria Syndrome cells, and does not cross react with mature lamin A.
- 产品特性
- The antibody is able to detect cleaved farnesylated prelamin A, while it does not recognize either full-length prelamin A or mature lamin A. This antibody can be used for the discrimination of prelamin A forms and to check the efficacy of potential therapeutic compounds acting on prelamin A processing.
- 纯化方法
- Polyclonal immunoglobulins purified by protein A affinity chromatography and stabilized with 5% of glycerol.
- 免疫原
- Farnesylated prelamin A C-terminus peptide
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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methanol fixing is suggested
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Supplied in 100 mM sodium citrate, 50 mM Tris and 0.05 % v/v glycerol
- 储存条件
- 4 °C
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- 抗原
- Prelamin A
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