HIV-1 Tat 抗体 (Biotin)
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- 抗原 See all HIV-1 Tat 抗体
- HIV-1 Tat
- 适用
- Human Immunodeficiency Virus (HIV)
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HIV-1 Tat antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- 特异性
- The antibody detects HIV1 tat protein and GST tat fusion protein. HIVI tat protein in sera or plasma and in cell culture supernatant
- 产品特性
- Tat is a regulatory protein of HIV-1 virus, well conserved among different isolates. Tat is produced early after infection and it's essential for virus replication and infectivity. Tat protein is also immunogenic and antibodies (Ab) against tat have been found to correlate with delayed disease progression and may exert protective effects by inhibiting both HIV-1 replication and the effects of extracellular tat. Moreover, tat is efficiently taken up by monocyte-derived dendritic cells, promotes their maturation and antigen presenting since it enters the major histocompatibility complex class I pathway. Finally, murine vaccination with a biologically active tat protein has been shown to be safe, immunogenic and elicits anti-tat neutralizing Ab and CTL.
- 纯化方法
- Purified by protein A affinity chromatography and conjugated by NHS-biotin.
- 免疫原
- Purified recombinant protein HIV-I tat expressed in E. coli
- Top Product
- Discover our top product HIV-1 Tat Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Supplied in PBS and 0.05 % v/v glycerol
- 储存条件
- 4 °C
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- 抗原
- HIV-1 Tat
- 别名
- HIV1 Tat (HIV-1 Tat 产品)
- 物质类
- Viral Protein
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