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5-Methylcytosine 抗体

WB, MeDIP, FACS, IF, DB, ICC, IHC, ELISA 宿主: 小鼠 Monoclonal 33D3 unconjugated
产品编号 ABIN2668982
发货至: 中国
  • 抗原
    5-Methylcytosine
    适用
    请咨询
    宿主
    • 22
    • 8
    • 3
    小鼠
    克隆类型
    • 24
    • 9
    单克隆
    标记
    • 16
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    非结合性
    应用范围
    • 19
    • 15
    • 13
    • 9
    • 8
    • 7
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Methylated DNA Immunoprecipitation (MeDIP), Flow Cytometry (FACS), Immunofluorescence (IF), Dot Blot (DB), Immunocytochemistry (ICC), Immunohistochemistry (IHC), ELISA
    纯化方法
    Protein A Chromatography
    免疫原
    Clone 33D3 recognizes the modified base 5-methylcytidine found in plant and vertebrate DNA.
    克隆位点
    33D3
    亚型
    IgG
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1 μg/μL
    缓冲液
    Purified IgG in 10 mM phosphate, 0.15 M NaCl and 0.01 % thimerosal. Thimerosal is highly toxic.
    注意事项

    Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

    储存条件
    -20 °C
    储存方法
    Antibodies in solution can be stored at -20 °C for 2 years.
    有效期
    6 months
  • Borghesan, Fusilli, Rappa, Panebianco, Rizzo, Oben, Mazzoccoli, Faulkes, Pata, Agodi, Rezaee, Minogue, Warren, Peterson, Sedivy, Douet, Buschbeck, Cappello, Mazza, Pazienza, Vinciguerra: "DNA Hypomethylation and Histone Variant macroH2A1 Synergistically Attenuate Chemotherapy-Induced Senescence to Promote Hepatocellular Carcinoma Progression." in: Cancer research, Vol. 76, Issue 3, pp. 594-606, (2016) (PubMed).

    McPherson, Fullston, Kang, Sandeman, Corbett, Owens, Lane: "Paternal under-nutrition programs metabolic syndrome in offspring which can be reversed by antioxidant/vitamin food fortification in fathers." in: Scientific reports, Vol. 6, pp. 27010, (2016) (PubMed).

    Banh, Iorio, Marcotte, Xu, Cojocari, Rahman, Pawling, Zhang, Sinha, Rose, Isasa, Zhang, Wu, Virtanen, Hitomi, Habu, Sidhu, Koizumi, Wilkins, Kislinger, Gygi, Schofield, Dennis, Wouters, Neel: "PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival during hypoxia." in: Nature cell biology, Vol. 18, Issue 7, pp. 803-813, (2016) (PubMed).

    Harrison, Cornett, Goldfarb, DaRosa, Li, Yan, Dickson, Guo, Cantu, Kaustov, Brown, Arrowsmith, Erie, Major, Klevit, Krajewski, Kuhlman, Strahl, Rothbart: "Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1." in: eLife, Vol. 5, (2016) (PubMed).

    Yang, Ma, Li, Zhang, Wan, Du, Li, Yang, Lu: "Iodine-125 irradiation inhibits invasion of gastric cancer cells by reactivating microRNA-181c expression." in: Oncology letters, Vol. 12, Issue 4, pp. 2789-2795, (2016) (PubMed).

    Ivanov, Kals, Kacevska, Barragan, Kasuga, Rane, Metspalu, Milani, Ingelman-Sundberg: "Ontogeny, distribution and potential roles of 5-hydroxymethylcytosine in human liver function." in: Genome biology, Vol. 14, Issue 8, pp. R83, (2014) (PubMed).

    Xu, Wang, Long, Zhang, Wei, Xing, Gu, Xie: "Stress-mediated p38 activation promotes somatic cell reprogramming." in: Cell research, Vol. 23, Issue 1, pp. 131-41, (2013) (PubMed).

    Colquitt, Allen, Barnea, Lomvardas: "Alteration of genic 5-hydroxymethylcytosine patterning in olfactory neurons correlates with changes in gene expression and cell identity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 36, pp. 14682-7, (2013) (PubMed).

    Bocker, Tuorto, Raddatz, Musch, Yang, Xu, Lyko, Breiling: "Hydroxylation of 5-methylcytosine by TET2 maintains the active state of the mammalian HOXA cluster." in: Nature communications, Vol. 3, pp. 818, (2012) (PubMed).

    Habib, Fares, Bourgeois, Bella, Bernardino, Hernandez-Blazquez, de Capoa, Niveleau: "DNA global hypomethylation in EBV-transformed interphase nuclei." in: Experimental cell research, Vol. 249, Issue 1, pp. 46-53, (1999) (PubMed).

  • 抗原
    5-Methylcytosine
    物质类
    Chemical
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