5-Hydroxymethylcytosine 抗体
(15 references)Quick Overview for 5-Hydroxymethylcytosine 抗体 (ABIN2668980)
抗原
适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Protein A Chromatography
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免疫原
- This 5-Hydroxymethylcytidine antibody was raised against 5-hydroxymethylcytidine conjugated to KLH and recognizes 5-hydroxymethylcytosine.
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亚型
- IgG
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anti-5-Hydroxymethylcytosine (5-hmC) antibody
5-hmC DB, hmeDIP, ICC, IF, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-5-Hydroxymethylcytosine (5-hmC) antibody5-hmC 适用: 人, 小鼠 DB, ICC, MeDIP, IF, IHC 宿主: 小鼠 Monoclonal 59-1 unconjugated
anti-5-Hydroxymethylcytosine (5-hmC) antibody5-hmC ELISA, DB, hmeDIP, ICC, IHC 宿主: 兔 Monoclonal RM236 unconjugated Recombinant Antibody
anti-5-Hydroxymethylcytosine (5-hmC) antibody5-hmC DB, hmeDIP, ICC, IF 宿主: 小鼠 Monoclonal 59-1 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1 μg/μL
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
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Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
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储存条件
- -20 °C
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储存方法
- Antibodies in solution can be stored at -20 °C for 2 years.
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有效期
- 6 months
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: "Tet1 and Tet2 Protect DNA Methylation Canyons against Hypermethylation." in: Molecular and cellular biology, Vol. 36, Issue 3, pp. 452-61, (2016) (PubMed).
: "5-Hydroxymethylcytosine discriminates between parathyroid adenoma and carcinoma." in: Clinical epigenetics, Vol. 8, pp. 31, (2016) (PubMed).
: "5-hydroxymethylcytosine marks promoters in colon that resist DNA hypermethylation in cancer." in: Genome biology, Vol. 16, pp. 69, (2015) (PubMed).
: "Reinforcement of STAT3 activity reprogrammes human embryonic stem cells to naive-like pluripotency. ..." in: Nature communications, Vol. 6, pp. 7095, (2015) (PubMed).
: "5-Carboxylcytosine levels are elevated in human breast cancers and gliomas." in: Clinical epigenetics, Vol. 7, pp. 88, (2015) (PubMed).
: "Redox-active quinones induces genome-wide DNA methylation changes by an iron-mediated and Tet-dependent mechanism." in: Nucleic acids research, Vol. 42, Issue 3, pp. 1593-605, (2014) (PubMed).
: "TET-mediated oxidation of methylcytosine causes TDG or NEIL glycosylase dependent gene reactivation." in: Nucleic acids research, Vol. 42, Issue 13, pp. 8592-604, (2014) (PubMed).
: "Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA." in: Nature, Vol. 506, Issue 7488, pp. 391-5, (2014) (PubMed).
: "Alteration of genic 5-hydroxymethylcytosine patterning in olfactory neurons correlates with changes in gene expression and cell identity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 36, pp. 14682-7, (2013) (PubMed).
: "Dynamics of 5-methylcytosine and 5-hydroxymethylcytosine during germ cell reprogramming." in: Cell research, Vol. 23, Issue 3, pp. 329-39, (2013) (PubMed).
: "Genome-wide analysis reveals TET- and TDG-dependent 5-methylcytosine oxidation dynamics." in: Cell, Vol. 153, Issue 3, pp. 692-706, (2013) (PubMed).
: "Naive pluripotency is associated with global DNA hypomethylation." in: Nature structural & molecular biology, Vol. 20, Issue 3, pp. 311-6, (2013) (PubMed).
: "Hydroxylation of 5-methylcytosine by TET2 maintains the active state of the mammalian HOXA cluster." in: Nature communications, Vol. 3, pp. 818, (2012) (PubMed).
: "Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells." in: Genes & development, Vol. 25, Issue 7, pp. 679-84, (2011) (PubMed).
: "Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies." in: Blood, Vol. 118, Issue 17, pp. 4509-18, (2011) (PubMed).
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: "Tet1 and Tet2 Protect DNA Methylation Canyons against Hypermethylation." in: Molecular and cellular biology, Vol. 36, Issue 3, pp. 452-61, (2016) (PubMed).
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- 5-Hydroxymethylcytosine (5-hmC)
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别名
- 5-Hydroxymethylcytosine
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物质类
- Chemical
抗原
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