电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

EZH2 抗体 (AA 1-370)

EZH2 适用: 人, 小鼠 IP, ChIP, ChIP-seq 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2668958
发货至: 中国
  • 抗原 See all EZH2 抗体
    EZH2 (Enhancer of Zeste Homolog 2 (EZH2))
    抗原表位
    • 16
    • 15
    • 15
    • 7
    • 7
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-370
    适用
    • 129
    • 62
    • 32
    • 8
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 103
    • 26
    • 1
    克隆类型
    • 96
    • 34
    多克隆
    标记
    • 61
    • 10
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EZH2 antibody is un-conjugated
    应用范围
    • 68
    • 40
    • 37
    • 25
    • 23
    • 17
    • 15
    • 13
    • 12
    • 9
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)
    纯化方法
    None
    免疫原
    This EZH2 antibody was raised against a recombinant fusion protein corresponding to amino acids 1-370 of mouse EZH2.
    Top Product
    Discover our top product EZH2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项

    Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

    储存条件
    -20 °C
    储存方法
    Antibodies in solution can be stored at -20 °C for 2 years.
    有效期
    6 months
  • LaFave, Béguelin, Koche, Teater, Spitzer, Chramiec, Papalexi, Keller, Hricik, Konstantinoff, Micol, Durham, Knutson, Campbell, Blum, Shi, Doud, Krivtsov, Chung, Khodos, de Stanchina, Ouerfelli et al.: "Loss of BAP1 function leads to EZH2-dependent transformation. ..." in: Nature medicine, Vol. 21, Issue 11, pp. 1344-9, (2015) (PubMed).

    Knutson, Kawano, Minoshima, Warholic, Huang, Xiao, Kadowaki, Uesugi, Kuznetsov, Kumar, Wigle, Klaus, Allain, Raimondi, Waters, Smith, Porter-Scott, Chesworth, Moyer, Copeland, Richon, Uenaka, Pollock et al.: "Selective inhibition of EZH2 by EPZ-6438 leads to potent antitumor activity in EZH2-mutant non-Hodgkin lymphoma. ..." in: Molecular cancer therapeutics, Vol. 13, Issue 4, pp. 842-54, (2014) (PubMed).

    Inoue, Kitaura, Togami, Nishimura, Enomoto, Uchida, Kagiyama, Kawabata, Nakahara, Izawa, Oki, Maehara, Isobe, Tsuchiya, Harada, Harada, Ochiya, Aburatani, Kimura, Thol, Heuser, Levine, Abdel-Wahab et al.: "Myelodysplastic syndromes are induced by histone methylation–altering ASXL1 mutations. ..." in: The Journal of clinical investigation, Vol. 123, Issue 11, pp. 4627-40, (2014) (PubMed).

    Kumar, Duester: "Retinoic acid controls body axis extension by directly repressing Fgf8 transcription." in: Development (Cambridge, England), Vol. 141, Issue 15, pp. 2972-7, (2014) (PubMed).

    Tong, He, Xie, Mochizuki, Liu, Mochizuki, Meng, Sun, Zhang, Guo, Hexner, Zhang: "Ezh2 regulates transcriptional and posttranslational expression of T-bet and promotes Th1 cell responses mediating aplastic anemia in mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 11, pp. 5012-22, (2014) (PubMed).

    Bender, Tang, Lindroth, Hovestadt, Jones, Kool, Zapatka, Northcott, Sturm, Wang, Radlwimmer, Højfeldt, Truffaux, Castel, Schubert, Ryzhova, Seker-Cin, Gronych, Johann, Stark, Meyer, Milde, Schuhmann et al.: "Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas. ..." in: Cancer cell, Vol. 24, Issue 5, pp. 660-72, (2013) (PubMed).

    Chng, Chang, Tan, Yang, Hong, Sng, Cheung: "A transcriptional repressor co-regulatory network governing androgen response in prostate cancers." in: The EMBO journal, Vol. 31, Issue 12, pp. 2810-23, (2012) (PubMed).

    Abdel-Wahab, Adli, LaFave, Gao, Hricik, Shih, Pandey, Patel, Chung, Koche, Perna, Zhao, Taylor, Park, Carroll, Melnick, Nimer, Jaffe, Aifantis, Bernstein, Levine: "ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression." in: Cancer cell, Vol. 22, Issue 2, pp. 180-93, (2012) (PubMed).

    Bredfeldt, Greathouse, Safe, Hung, Bedford, Walker: "Xenoestrogen-induced regulation of EZH2 and histone methylation via estrogen receptor signaling to PI3K/AKT." in: Molecular endocrinology (Baltimore, Md.), Vol. 24, Issue 5, pp. 993-1006, (2010) (PubMed).

  • 抗原
    EZH2 (Enhancer of Zeste Homolog 2 (EZH2))
    别名
    EZH2 (EZH2 产品)
    别名
    ENX-1 antibody, ENX1 antibody, EZH1 antibody, EZH2b antibody, KMT6 antibody, KMT6A antibody, WVS antibody, WVS2 antibody, eya2 antibody, im:7149338 antibody, zgc:136376 antibody, zgc:152758 antibody, EZH2 antibody, enx-1 antibody, enx1 antibody, ezh1 antibody, kmt6 antibody, xez antibody, Enx-1 antibody, Enx1h antibody, mKIAA4065 antibody, ezh2 antibody, olezh2 antibody, enhancer of zeste 2 polycomb repressive complex 2 subunit antibody, enhancer of zeste 2 polycomb repressive complex 2 subunit L homeolog antibody, enhancer of zeste 2 polycomb repressive complex 2 subunit S homeolog antibody, EZH2 antibody, ezh2 antibody, Ezh2 antibody, ezh2.L antibody, ezh2.S antibody
    分子量
    96 kDa
    基因ID
    2146
    途径
    Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation
You are here:
客服