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HDAC4 抗体 (AA 194-209)

Name: HDAC4 抗体 (AA 194-209)
SKU: ABIN2668313
Availability: OutOfStock

HDAC4 适用: 人, 小鼠 WB, ChIP, ChIP-seq 宿主: 兔 Polyclonal unconjugated

HDAC4 antibody (pAb) tested by Western blot. (HDAC4 抗体 (AA 194-209))

ChIP-seq

2 images

(9 references)

产品编号 ABIN2668313

发货至: 中国

Datasheet as PDF

抗原 See all HDAC4 抗体

HDAC4 (Histone Deacetylase 4 (HDAC4))
抗原表位
15

12

9

8

7

6

5

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 194-209
适用
102

46

33

6

6

4

4

4

3

2

1

1

1

1
人, 小鼠
宿主
91

12

1
兔
Compatible Secondaries
克隆类型
92

12
多克隆
标记
65

7

6

5

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This HDAC4 antibody is un-conjugated
应用范围
75

46

24

15

13

13

11

8

6

4

3

3

2

2

1

1
Western Blotting (WB), Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)

纯化方法

Affinity Purified

免疫原

This HDAC4 antibody was raised against a synthetic peptide corresponding to amino acid residues 194-209 of human HDAC4.

亚型

IgG

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anti-Histone Deacetylase 4 (HDAC4) (pSer632) antibody
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anti-Histone Deacetylase 4 (HDAC4) (AA 530-630) antibody
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anti-Histone Deacetylase 4 (HDAC4) (Ser632) antibody
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anti-Histone Deacetylase 4 (HDAC4) (Tyr493) antibody
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应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
浓度

0.5 μg/μL

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

储存条件

-80 °C

储存方法

Antibodies in solution can be stored at -80 °C for 2 years.

有效期

6 months
Liu, Gu, Feng, Yang, Zhu, Lu, Qi: "Both HDAC5 and HDAC6 are required for the proliferation and metastasis of melanoma cells." in: Journal of translational medicine, Vol. 14, pp. 7, (2016) (PubMed).

Isaacs, Antony, Dalrymple, Brennen, Gerber, Hammers, Wissing, Kachhap, Luo, Xing, Björk, Olsson, Björk, Leanderson: "Tasquinimod Is an Allosteric Modulator of HDAC4 survival signaling within the compromised cancer microenvironment." in: Cancer research, Vol. 73, Issue 4, pp. 1386-99, (2013) (PubMed).

Keedy, Archin, Gates, Espeseth, Hazuda, Margolis: "A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression." in: Journal of virology, Vol. 83, Issue 10, pp. 4749-56, (2009) (PubMed).

Mottet, Bellahcène, Pirotte, Waltregny, Deroanne, Lamour, Lidereau, Castronovo: "Histone deacetylase 7 silencing alters endothelial cell migration, a key step in angiogenesis." in: Circulation research, Vol. 101, Issue 12, pp. 1237-46, (2007) (PubMed).

Sayeed, Konduri, Liu, Bansal, Li, Das: "Estrogen receptor alpha inhibits p53-mediated transcriptional repression: implications for the regulation of apoptosis." in: Cancer research, Vol. 67, Issue 16, pp. 7746-55, (2007) (PubMed).

Testoni, Mantovani: "Mechanisms of transcriptional repression of cell-cycle G2/M promoters by p63." in: Nucleic acids research, Vol. 34, Issue 3, pp. 928-38, (2006) (PubMed).

Basile, Mantovani, Imbriano: "DNA damage promotes histone deacetylase 4 nuclear localization and repression of G2/M promoters, via p53 C-terminal lysines." in: The Journal of biological chemistry, Vol. 281, Issue 4, pp. 2347-57, (2006) (PubMed).

Imbriano, Gurtner, Cocchiarella, Di Agostino, Basile, Gostissa, Dobbelstein, Del Sal, Piaggio, Mantovani: "Direct p53 transcriptional repression: in vivo analysis of CCAAT-containing G2/M promoters." in: Molecular and cellular biology, Vol. 25, Issue 9, pp. 3737-51, (2005) (PubMed).

Caretti, Salsi, Vecchi, Imbriano, Mantovani: "Dynamic recruitment of NF-Y and histone acetyltransferases on cell-cycle promoters." in: The Journal of biological chemistry, Vol. 278, Issue 33, pp. 30435-40, (2003) (PubMed).
抗原

HDAC4 (Histone Deacetylase 4 (HDAC4))

别名

HDAC4 (HDAC4 产品)

分子量

140 kDa

基因ID

9759

途径

Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process