GPR177/WLS 抗体
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- 抗原 See all GPR177/WLS (WLS) 抗体
- GPR177/WLS (WLS) (Wntless Homolog (WLS))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This GPR177/WLS antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 克隆位点
- YJ5
- 亚型
- IgG1
- Top Product
- Discover our top product WLS Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Upon receipt, store undiluted between 2°C and 8°C.
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- 抗原
- GPR177/WLS (WLS) (Wntless Homolog (WLS))
- 别名
- Wntless (WLS 产品)
- 背景
- Wnt signaling plays important roles in embryonic development and cancer formation. Wntless (GPR177) is a putative G-protein coupled receptor that regulates Wnt's trafficking and secretion. It can regulate the expression, subcellular location, binding, and organelle-specific association of Wnt proteins. In mammals, Wntless is mainly expressed in submucosa, muscle, ganglia, and nerve cells of the large intestines. Overexpression of Wntless may activate the NF-κB signaling pathway in cancer cells.
- 途径
- WNT signaling
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