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BCL11B 抗体

BCL11B 适用: 人 FACS 宿主: 大鼠 Monoclonal 25B6 unconjugated
产品编号 ABIN2666299
发货至: 中国
  • 抗原 See all BCL11B 抗体
    BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))
    适用
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    宿主
    • 46
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    大鼠
    克隆类型
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    单克隆
    标记
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    This BCL11B antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS)
    交叉反应
    小鼠, 斑马鱼
    交叉反应 (详细)
    Mouse, Zebrafish
    纯化方法
    Protein G affinity purified.
    克隆位点
    25B6
    亚型
    IgG
    Top Product
    Discover our top product BCL11B Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Hepes-buffered solution, pH 7.5, 0.02 % Sodium azide .
    储存条件
    4 °C
    储存方法
    Upon receipt, store undiluted between 2°C and 8°C.
  • 抗原
    BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))
    别名
    Bcl11b (BCL11B 产品)
    别名
    BCL11B antibody, 9130430L19Rik antibody, AI604821 antibody, B630002E05Rik antibody, BCL-11B antibody, Ctip2 antibody, Rit1 antibody, ATL1 antibody, ATL1-alpha antibody, ATL1-beta antibody, ATL1-delta antibody, ATL1-gamma antibody, CTIP-2 antibody, CTIP2 antibody, RIT1 antibody, ZNF856B antibody, hRIT1-alpha antibody, B-cell CLL/lymphoma 11B antibody, B cell leukemia/lymphoma 11B antibody, B-cell CLL/lymphoma 11B (zinc finger protein) antibody, BCL11B antibody, Bcl11b antibody
    背景
    The transcription factor Bcl11b is expressed in thymus, mainly T cells. It is indispensable for T lineage development. When Bcl11b was deleted, T cells from all developmental stages acquired NK cell properties and concomitantly lost or decreased T cell-associated gene expression. These induced T-to-natural killer (ITNK) cells, which were morphologically and genetically similar to conventional NK cells, killed tumor cells in vitro, and effectively prevented tumor metastasis in vivo. Therefore, ITNKs may represent a new cell source for cell-based therapies.
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