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IRF9 抗体

This anti-IRF9 antibody is a 小鼠 单克隆 antibody detecting IRF9 in FACS. Suitable for 人.
产品编号 ABIN2666230
发货至: 中国

Quick Overview for IRF9 抗体 (ABIN2666230)

抗原

See all IRF9 抗体
IRF9 (Interferon Regulatory Factor 9 (IRF9))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This IRF9 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

5A3A39
  • 纯化方法

    Affinity purified.

    亚型

    IgG2b kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Upon receipt, store undiluted 2°C and 8°C.
  • 抗原

    IRF9 (Interferon Regulatory Factor 9 (IRF9))

    别名

    IRF9

    背景

    IRF9 is a member of the IRF family of transcription factors and plays an important role in IFN signaling pathways and anti-viral immune responses. Type I and type III interferon stimulation induces phosphorylation and heterodimerization of STAT1 and STAT2. The activated STAT1:STAT2 heterodimer recruits IRF9 and forms a heterotrimeric complex termed IFN-stimulated gene factor 3 (ISGF3). The ISGF3 complex, in turn, translocates to the nucleus and transactivates IFN-inducible genes. The IRF9 protein in the ISGF3 complex is responsible for the recognition of IFN-stimulated response elements (ISRE). Mice lacking IRF9 fail to induce the expression of IFN regulated genes in response to type I interferon stimulation, indicating that IRF9 is crucial in mediating interferon signaling.

    途径

    JAK/STAT Signaling, Interferon-gamma Pathway, Hepatitis C
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