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- 抗原
- Nuclear Factor kappa B p50 (NFkB p50)
- 适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- 非结合性
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应用范围
- Biochemical Assay (BCA)
- 纯化方法
- The antibody was purified by affinity chromatography.
- 克隆位点
- 4D1
- 亚型
- IgG1 kappa
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anti-Nuclear Factor kappa B p50 (NFkB p50) (N-Term) antibody
适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide. Final antibody concentration is 0.5 mg/mL.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Upon receipt, store between 2°C and 8°C.
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- 抗原
- Nuclear Factor kappa B p50 (NFkB p50)
- 别名
- NF-B p50
- 别名
- NF-KB1 antibody, NF-kappaB antibody, NF-kappaB1 antibody, p105 antibody, p50 antibody, p50/p105 antibody, nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 antibody, Nfkb1 antibody
- 背景
- NF-κB/p50 (nuclear factor kappa light chain enhancer in B cells p50, NF-κB1) is a member of the Rel/dorsal family. This ubiquitously expressed nuclear protein is one subunit of the NF-kappa B complex consisting of a 65 kD transactivating subunit and a 50 kD DNA binding subunit. Both subunits are derived from larger precursor proteins. NF-κB acts as a transcriptional activator and was originally identified as an activator of kappa light chain in B cells. NF-κB/p50 is bound (with p65) to IκB inhibitor in cytoplasm in inactive form. Phosphorylation of IκB releases and NF- κB which goes to the nucleus to activate gene expression. NF-κB can be activated with LPS, TNF-α, phorbol ester, or IL-1. The 4D1 monoclonal antibody reacts with human NF-κB p50 and has been shown to be useful for Western blotting.
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