×
我们推荐在您的浏览器上开启Javascript,以获得最佳效果。
TNF alpha 抗体
TNF alpha
适用: 人
FACS
宿主: 小鼠
Monoclonal
MAb11
unconjugated
TNF alpha抗体详情
(hide)
抗原
See all TNF alpha 抗体
TNF alpha
(Tumor Necrosis Factor alpha (TNF alpha))
适用
All reactivities for TNF alpha 抗体
人
宿主
All hosts for TNF alpha 抗体
小鼠
克隆类型
All clonalities for TNF alpha 抗体
单克隆
标记
All conjugates for TNF alpha 抗体
This TNF alpha antibody is un-conjugated
应用范围
All applications for TNF alpha 抗体
Flow Cytometry (FACS)
交叉反应
Chimpanzee, Baboon, Cynomolgus, 猕猴, 猪, Pigtailed Macaque, Sooty mangabey (Cercocebus atys)
纯化方法
The antibody was purified by affinity chromatography.
克隆位点
MAb11
亚型
IgG1 kappa
Top Product
Discover our top product TNF alpha Primary Antibody
Alternatives
(show)
使用细节
(hide)
应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
(hide)
浓度
0.5 mg/mL
缓冲液
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C
储存方法
The antibody solution should be stored undiluted between 2°C and 8°C.
TNF alpha目标详情
(hide)
抗原
TNF alpha
(Tumor Necrosis Factor alpha (TNF alpha))
别名
TNF-alpha (TNF alpha 产品 )
别名
DIF antibody, TNF-alpha antibody, TNFA antibody, TNFSF2 antibody, RATTNF antibody, Tnfa antibody, tnf antibody, TNF-a antibody, TNFalpha antibody, Tnfsf1a antibody, TNFa antibody, cTNF antibody, Tnf-alpha antibody, tnfa-like antibody, TNF-ALPHA antibody, dif antibody, tnfa antibody, xtnf antibody, tnfsf2 antibody, tnf-alpha antibody, Cachectin antibody, tumor necrosis factor antibody, tumor necrosis factor b (TNF superfamily, member 2) antibody, tumor necrosis factor alpha antibody, tumor necrosis factor a (TNF superfamily, member 2) antibody, TNF antibody, Tnf antibody, tnf antibody, tnfb antibody, tnf-alpha antibody, LOC103694380 antibody, tnfa antibody
背景
TNF-α is secreted by macrophages, monocytes, neutrophils, T cells (principally CD4+), and NK cells. Many transformed cell lines also secrete TNF-α. Monomeric human TNF-α is a 157 amino acid protein (non-glycosylated) with a reported molecular weight of 17 kD. TNF-α forms multimeric complexes, stable trimers are most common in solution. A 26 kD membrane form of TNF-α has also been described. TNF-α binding to surface receptors elicits a wide array of biological activities including: cytolysis and cytostasis of many tumor cell lines in vitro, hemorraghic necrosis of tumors in vivo, increased fibroblast proliferation, and enhanced chemotaxis and phagocytosis in neutrophils.
途径
NF-kappaB Signaling , Apoptosis , Caspase Cascade in Apoptosis , TLR signaling , Cellular Response to Molecule of Bacterial Origin , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Production of Molecular Mediator of Immune Response , Positive Regulation of Endopeptidase Activity , Hepatitis C , Protein targeting to Nucleus , Inflammasome
Recently viewed
(hide)