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- 抗原 See all SIGLEC8 抗体
- SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SIGLEC8 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 纯化方法
- The antibody was purified by affinity chromatography.
- 克隆位点
- 7C9
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product SIGLEC8 Primary Antibody
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anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (AA 18-121) antibody
SIGLEC8 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (AA 18-121) antibodySIGLEC8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H1 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (Internal Region) antibodySIGLEC8 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (AA 70-336) antibodySIGLEC8 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) antibodySIGLEC8 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (Internal Region) antibodyVerified SIGLEC8 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (Extracellular Domain) antibodySIGLEC8 适用: 人 ELISA, IP, FACS 宿主: 小鼠 Monoclonal 7C9 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (Extracellular Domain) antibody (PE)SIGLEC8 适用: 人 FACS 宿主: 小鼠 Monoclonal 7C9 PE
anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (AA 17-363) antibodySIGLEC8 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8) (AA 70-336) antibodySIGLEC8 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
- 别名
- Siglec-8 (SIGLEC8 产品)
- 别名
- SAF2 antibody, SIGLEC-8 antibody, SIGLEC8L antibody, SIGLEC8 antibody, sialic acid binding Ig like lectin 8 antibody, sialic acid-binding Ig-like lectin 8 antibody, SIGLEC8 antibody, LOC506364 antibody
- 背景
- Siglec-8 is a lectin specific for 6'-sulfo-sLex and a member of the Ig-superfamily. It is expressed almost exclusively in eosinophils, however, basophils and mast cells can express it to a lower degree. Siglec-8 is a 54 kD transmembranal protein, the extracellular domain has one V-set Ig-like domain and two C2-set domains. The cytoplasmic domain has two immunoreceptor tyrosine-based inhibitor motifs (ITIM) that recruit SH2-family phosphatases after tyrosine phosphorylation. There are reports that siglec-8 inhibits the release of histamine and prostaglandin D2 mediated by the IgEFcR. This molelcule is also involved in the induction of apoptosis.
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