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IL23 抗体

IL23 适用: 小鼠 FACS 宿主: 小鼠 Monoclonal MMp19B2 unconjugated
产品编号 ABIN2665147
发货至: 中国
  • 抗原 See all IL23 抗体
    IL23 (Interleukin 23 (IL23))
    适用
    • 20
    • 6
    • 5
    • 1
    • 1
    小鼠
    宿主
    • 18
    • 8
    • 1
    • 1
    小鼠
    克隆类型
    • 19
    • 9
    单克隆
    标记
    • 22
    • 4
    • 2
    This IL23 antibody is un-conjugated
    应用范围
    • 23
    • 9
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    MMp19B2
    亚型
    IgG2b kappa
    Top Product
    Discover our top product IL23 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    IL23 (Interleukin 23 (IL23))
    别名
    IL-23 (IL23 产品)
    别名
    IL-23 antibody, p19 antibody, SGRF antibody, il23p19 antibody, interleukin 23, alpha subunit p19 antibody, interleukin 23 subunit alpha antibody, Il23a antibody, IL23A antibody
    背景
    Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12.IL-23 is secreted by activated macrophages and dendritic cells.Human and mouse p19 share 70 % aa sequence identity. The functional IL-23 receptor complex consists of two receptor subunits, a β1 subunit shared with the IL-12 receptor (IL-12R β1) and a β2-like subunit with STAT4 binding domain, termed the IL-23-specific receptor subunit (IL-23R).IL-23 has been shown to enhance IFN-γ production by memory T cells.Additionally, mouse IL-23 (but not IL-12) can activate mouse memory T cells to produce the potent proinflammatory cytokine IL-17.IL-23 has been shown to be upregulated in certain autoimmune diseases and promote immunity in response to some viral and mycobacterial infections.
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