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IL12 抗体
IL12
适用: 人
FACS
宿主: 小鼠
Monoclonal
7B12
unconjugated
IL12抗体详情
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抗原
See all IL12 抗体
IL12
(Interleukin 12 (IL12))
适用
All reactivities for IL12 抗体
人
宿主
All hosts for IL12 抗体
小鼠
克隆类型
All clonalities for IL12 抗体
单克隆
标记
All conjugates for IL12 抗体
This IL12 antibody is un-conjugated
应用范围
All applications for IL12 抗体
Flow Cytometry (FACS)
纯化方法
The antibody was purified by affinity chromatography.
克隆位点
7B12
亚型
IgG1
Top Product
Discover our top product IL12 Primary Antibody
Alternatives
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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浓度
0.5 mg/mL
缓冲液
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C
储存方法
The antibody solution should be stored undiluted between 2°C and 8°C.
IL12目标详情
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抗原
IL12
(Interleukin 12 (IL12))
别名
IL-12 (IL12 产品 )
别名
CLMF antibody, CLMF2 antibody, IL-12B antibody, NKSF antibody, NKSF2 antibody, p40 antibody, Il-12b antibody, Il12p40 antibody, Il-12p40 antibody, Il12 antibody, IL-12p40 antibody, IL-12 antibody, LOC100217488 antibody, IL-12p35 antibody, Il-12a antibody, Ll12a antibody, p35 antibody, IL12p40 antibody, IL12B antibody, IL-12 p35 antibody, interleukin 12B antibody, interleukin 12A antibody, interleukin 12b antibody, interleukin 12a antibody, Interleukin 12 level antibody, IL12B antibody, IL12A antibody, Il12b antibody, Il12a antibody, IL12 antibody, il12a antibody
背景
Bioactive IL-12 is a potent regulator of cell-mediated immune responses and key mediator of Th1 cell development. Bioactive IL-12 is secreted by activated B lymphocytes, dendritic cells and macrophages as a 70 kD heterodimeric glycoprotein comprised of disulfide-bonded 35 kD and 40 kD subunits. The disulfide-linked p40 homodimer can bind to IL-12 receptors and antagonize the activities of bioactive IL-12. The 7B12 antibody reacts with human IL-12 p70 heterodimer, but shows no reactivity with IL-12 p35 or p40 monomer. The 7B12 has high affinity to human IL-12 p70 heterodimer.
途径
JAK/STAT Signaling , TLR signaling , Cellular Response to Molecule of Bacterial Origin , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Activated T Cell Proliferation , Cancer Immune Checkpoints , Inflammasome
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