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- 抗原 See all Keratin 7/17 (KRT7/17) 抗体
- Keratin 7/17 (KRT7/17)
- 适用
- 人, Cow, Pig
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Keratin 7/17 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 无交叉反应
- 小鼠, 大鼠, 兔
- 纯化方法
- The antibody was purified by affinity chromatography.
- 克隆位点
- C-46
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product KRT7/17 Primary Antibody
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anti-Keratin 7/17 (KRT7/17) antibody
KRT7/17 适用: 人, Cow, Pig WB, IP, ICC, IHC (p) 宿主: 小鼠 Monoclonal C-46 unconjugated
anti-Keratin 7/17 (KRT7/17) antibodyKRT7/17 适用: 人, Cow WB, IHC, FACS, IF, StM 宿主: 小鼠 Monoclonal C-46 unconjugated
anti-Keratin 7/17 (KRT7/17) antibodyKRT7/17 适用: 人, Cow, Pig WB, IHC, IP, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide at 0.5 mg/mL.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- Keratin 7/17 (KRT7/17)
- 别名
- Cytokeratin 7/17 (KRT7/17 产品)
- 别名
- KRT7 antibody, CK7 antibody, keratin 7 antibody, KRT7 antibody
- 背景
- Cytokeratins are proteins that are involved in the cytoskeleton. The cytokeratin proteins are heterotetramers composed of two type I and two type II subunits. Cytokeratin 17 is a type I protein and cytokeratin 7 is a type II intermediate filament protein, each protein contains three coiled-coil domains. Cytokeratin 7 has an approximate molecular weight of 54 kD, cytokeratin 17 has an approximate molecular weight of 46 kD. Cytokeratin 17 is expressed in the basal cells of complex epithelia, but not in stratified or simple epithelia. Cytokeratin 7 is expressed in the epidermis, bronchus, and mesothelium but not in the colon, exocervix or liver. Mutations in cytokeratin 17 have been shown to result in pachyonychia congenital. Cytokeratin 17 has been shown to interact with the EGF receptor. Cytokeratin 7 has been shown to interact with the EGF receptor and heat shock protein 70 kD1A. The C-46 monoclonal antibody recognizes human, bovine and porcine (but not mouse, rat, or rabbit) cytokeratin 7 and cytokeratin 17 and is useful for Western blotting.This antibody has also been reported to be useful for immunoprecipitation, immunohistochemistry (paraffin sections), and immunocytochemistry.
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