TAD antibody, cTADS antibody, MGC82176 antibody, CRTAM antibody, CD355 antibody, cytotoxic and regulatory T-cell molecule antibody, cytotoxic and regulatory T-cell molecule L homeolog antibody, cytotoxic and regulatory T cell molecule antibody, CRTAM antibody, crtam.L antibody, Crtam antibody
背景
Class-I MHC-restricted T-cell associated molecule (CRTAM), designated as CD355, is an Ig domain like type I transmembrane receptor, which belongs to the nectin family. In the immune system, CRTAM is strictly expressed on activated NK cells and activated CD8-positive T cells. By binding its ligand Nectin-like molecule 2 (Necl2), CRTAM plays an important role in mediating cell adhesion and migration.