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RANKL 抗体
TNFSF11
适用: 人
IHC, FACS
宿主: 小鼠
Monoclonal
MIH24
unconjugated
RANKL抗体详情
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抗原
See all RANKL (TNFSF11) 抗体
RANKL (TNFSF11)
(Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))
适用
All reactivities for RANKL 抗体
人
宿主
All hosts for RANKL 抗体
小鼠
克隆类型
All clonalities for RANKL 抗体
单克隆
标记
All conjugates for RANKL 抗体
This RANKL antibody is un-conjugated
应用范围
All applications for RANKL 抗体
Immunohistochemistry (IHC), Flow Cytometry (FACS)
纯化方法
The antibody was purified by affinity chromatography.
克隆位点
MIH24
亚型
IgG2b kappa
Top Product
Discover our top product TNFSF11 Primary Antibody
Alternatives
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anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) (AA 210-317) antibody
TNFSF11
适用: 人, 小鼠, 大鼠, 兔
WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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浓度
0.5 mg/mL
缓冲液
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C
储存方法
The antibody solution should be stored undiluted between 2°C and 8°C.
RANKL目标详情
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抗原
RANKL (TNFSF11)
(Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))
别名
CD254 (TNFSF11 产品 )
别名
CD254 antibody, ODF antibody, OPGL antibody, OPTB2 antibody, RANKL antibody, TRANCE antibody, hRANKL2 antibody, sOdf antibody, TNFSF11 antibody, Ly109l antibody, OPG antibody, Trance antibody, cd254 antibody, odf antibody, opgl antibody, optb2 antibody, rankl antibody, sodf antibody, tnfsf11 antibody, trance antibody, TNF superfamily member 11 antibody, tumor necrosis factor (ligand) superfamily, member 11 antibody, TNF receptor superfamily member 11b antibody, TNF superfamily member 11 L homeolog antibody, TNFSF11 antibody, Tnfsf11 antibody, TNFRSF11B antibody, tnfsf11.L antibody
背景
Human CD254, also known as RANKL, TRANCE, and OPGL, is a type II transmembrane protein in the TNF superfamily that has two forms: a membrane-anchored protein and a secreted protein. Its extracellular domain is related to TRAIL, FasL, and TNF. CD254 is expressed on osteoclasts and activated T cells. It has been implicated in the regulation of the interactions between T cells and dendritic cells. It plays an important role in osteoclast differentiation and bone resorption. CD254 activates JNK and NF-κB and induces the expression of IL-1, IL-6, IL-12, and IL-15 in dendritic cells.
途径
NF-kappaB Signaling
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