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CD213alpha2 抗体

适用: 人 FACS 宿主: 小鼠 Monoclonal SHM38 unconjugated
产品编号 ABIN2664400
发货至: 中国
  • 抗原
    CD213alpha2
    适用
    宿主
    小鼠
    克隆类型
    单克隆
    应用范围
    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    SHM38
    亚型
    IgG1 kappa
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    CD213alpha2
    背景
    CD213a2, also known as IL-13Rα2, is a type I transmembrane protein and member of the hematopoietin family. IL13Ra2 is the high affinity receptor for IL-13, but it possibly acts as a decoy receptor to antagonize IL-13Rα 1/IL-4Ra-mediated IL-13 biological functions. IL13Rα2 is expressed by fibroblasts, smooth muscle cells, keratinocytes and activated B cells. However, its presence on the cell surface is highly regulated. CD213a2 is also expressed in various types of cancer which makes it an attractive therapeutic target.
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