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LY75/DEC-205 抗体

LY75 适用: 人, 小鼠, 大鼠 ICFC 宿主: 小鼠 Monoclonal HD83 unconjugated
产品编号 ABIN2664380
发货至: 中国
  • 抗原 See all LY75/DEC-205 (LY75) 抗体
    LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))
    适用
    • 42
    • 25
    • 6
    • 5
    • 1
    人, 小鼠, 大鼠
    宿主
    • 34
    • 20
    • 6
    • 1
    • 1
    小鼠
    克隆类型
    • 34
    • 27
    • 1
    单克隆
    标记
    • 26
    • 9
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This LY75/DEC-205 antibody is un-conjugated
    应用范围
    • 22
    • 19
    • 17
    • 15
    • 12
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Intracellular Flow Cytometry (ICFC)
    交叉反应
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    HD83
    亚型
    IgG1 kappa
    Top Product
    Discover our top product LY75 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))
    别名
    CD205 (LY75 产品)
    别名
    LY75 antibody, MGC140308 antibody, DEC205 antibody, im:7150926 antibody, si:dkey-78p20.2 antibody, LYT75 antibody, CD205 antibody, DEC-205 antibody, CLEC13B antibody, GP200-MR6 antibody, LY-75 antibody, RGD1565962 antibody, Ly-75 antibody, lymphocyte antigen 75 antibody, CD205 protein antibody, CD302 antigen antibody, LY75 antibody, Cyan7822_2917 antibody, LY5 antibody, ly75 antibody, cd205 antibody, LOC100380704 antibody, LOC100433861 antibody, LOC100483541 antibody, Ly75 antibody
    背景
    CD205, also known as DEC-205 and LY75, belongs to the macrophage mannose receptor (MMR) family of C-type lectins. Both human and mouse CD205 share multiple similar structures: an N-terminal cysteine-rich domain, a fibronectin type II domain, and a series of 10 tandemly repeated C-type like domains (CTLDs). CD205 is highly expressed on dendritic cells and thymic cortical epithelial cells in humans and mice. It also can be detected on T and B cells, monocytes, neutrophils, and epithelial cells. CD205 is a novel endocytic receptor used by dendritic cells and thymic epithelial cells to direct captured antigens from the extracellular space to specialized antigen processing areas. It mediates antigen uptake and presentation and cross-presentation to T cells. It has been reported that CD205 acts as a recognition receptor for dying cells, which potentially provides an important pathway for the uptake of self-antigen in the intrathymic environment, and is involved in peripheral tolerance.
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