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SIRPA 抗体

SIRPA 适用: 大鼠 FACS, IHC, IF 宿主: 小鼠 Monoclonal OX-41 unconjugated
产品编号 ABIN2664292
发货至: 中国
  • 抗原 See all SIRPA 抗体
    SIRPA (Signal-Regulatory Protein alpha (SIRPA))
    适用
    • 72
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    大鼠
    宿主
    • 58
    • 33
    • 1
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    小鼠
    克隆类型
    • 57
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    单克隆
    标记
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    This SIRPA antibody is un-conjugated
    应用范围
    • 57
    • 46
    • 20
    • 18
    • 13
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    • 11
    • 10
    • 9
    • 2
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    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    OX-41
    亚型
    IgG2a kappa
    Top Product
    Discover our top product SIRPA Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    SIRPA (Signal-Regulatory Protein alpha (SIRPA))
    别名
    CD172a (SIRPA 产品)
    别名
    BIT antibody, CD172A antibody, MFR antibody, MYD-1 antibody, P84 antibody, PTPNS1 antibody, SHPS1 antibody, SIRP antibody, SIRPA antibody, SIRP-A1 antibody, SIRP-B1 antibody, AI835480 antibody, Bit antibody, CD172a antibody, Ptpns1 antibody, SHP-1 antibody, SHPS-1 antibody, swc3 antibody, signal regulatory protein alpha antibody, myeloperoxidase antibody, signal-regulatory protein alpha antibody, tyrosine-protein phosphatase non-receptor type substrate 1 antibody, SIRPA antibody, MPO antibody, LOC458039 antibody, LOC100400378 antibody, LOC100590224 antibody, Sirpa antibody
    背景
    Rat CD172a, also known as a signal-regulatory protein α (SIRPα), is a 75-110 kD transmembrane glycoprotein involved in the receptor tyrosine kinase coupled signaling pathway. It belongs to the Ig superfamily primarily expressed on monocytes/macrophages, granulocytes, dendritic cells and neurons. CD172a serves as a substrate of activated receptor ttyrosine kinases (RTKs). The interaction of the CD172a intracellular domain with SHP-1 and SHP-2 displays negative signaling in the regulation of leukocyte adhesion and transmigration, T cell activation, macrophage fusion and phagocytosis. CD47 (IAP) is an extracellular ligand for CD172a.
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