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CD11b 抗体
ITGAM
适用: 人
MA
宿主: 小鼠
Monoclonal
ICRF44
unconjugated
CD11b抗体详情
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抗原
See all CD11b (ITGAM) 抗体
CD11b (ITGAM)
(Integrin alpha M (ITGAM))
适用
All reactivities for CD11b 抗体
人
宿主
All hosts for CD11b 抗体
小鼠
克隆类型
All clonalities for CD11b 抗体
单克隆
标记
All conjugates for CD11b 抗体
This CD11b antibody is un-conjugated
应用范围
All applications for CD11b 抗体
Multiplex Assay (MA)
交叉反应
Chimpanzee, Baboon, Cynomolgus, 猕猴, Marmoset, 猪
纯化方法
The antibody was purified by affinity chromatography.
克隆位点
ICRF44
亚型
IgG1 kappa
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Discover our top product ITGAM Primary Antibody
Alternatives
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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浓度
1.0 mg/mL
缓冲液
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and EDTA.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C
储存方法
The antibody solution should be stored undiluted between 2°C and 8°C.
CD11b目标详情
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抗原
CD11b (ITGAM)
(Integrin alpha M (ITGAM))
别名
CD11b (ITGAM 产品 )
别名
CD11b/CD18 antibody, CR3 antibody, CR3A antibody, Cd11b antibody, F730045J24Rik antibody, Ly-40 antibody, MAC1 antibody, Mac-1 antibody, Mac-1a antibody, CD11B antibody, MAC-1 antibody, MAC1A antibody, MO1A antibody, SLEB6 antibody, C3bi antibody, integrin subunit alpha M antibody, integrin alpha M antibody, integrin, alpha M (complement component 3 receptor 3 subunit) antibody, integrin alpha-M antibody, ITGAM antibody, Itgam antibody, LOC100351865 antibody
背景
CD11b is a 165-170 kD type I transmembrane glycoprotein also known as αM integrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin β2 (CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and factor X.
途径
Apoptosis , Activation of Innate immune Response , Toll-Like Receptors Cascades , Activated T Cell Proliferation
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