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Integrin beta 7 抗体 (PE)

ITGB7 适用: 人, 小鼠 FACS 宿主: 大鼠 Monoclonal FIB504 PE
产品编号 ABIN2663810
发货至: 中国
  • 抗原 See all Integrin beta 7 (ITGB7) 抗体
    Integrin beta 7 (ITGB7)
    适用
    • 72
    • 21
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 52
    • 10
    • 8
    • 4
    • 1
    大鼠
    克隆类型
    • 56
    • 17
    • 2
    单克隆
    标记
    • 32
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    This Integrin beta 7 antibody is conjugated to PE
    应用范围
    • 43
    • 28
    • 19
    • 13
    • 13
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
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    Flow Cytometry (FACS)
    交叉反应
    Chimpanzee, Baboon, Cynomolgus, 猕猴
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    克隆位点
    FIB504
    亚型
    IgG2a kappa
    Top Product
    Discover our top product ITGB7 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    Integrin beta 7 (ITGB7)
    别名
    Integrin Beta7 (ITGB7 产品)
    别名
    Ly69 antibody, integrin beta 7 antibody, integrin subunit beta 7 antibody, integrin, beta 7 antibody, Itgb7 antibody, ITGB7 antibody
    背景
    Integrin β7 is a 130 kD glycoprotein also known as integin βp. It is a member of the Ig superfamily. In association with integrin α4 or αE chain, β7 forms α4/β7 or αE/β7 heterodimer. α4/β7 (CD49d/β7, LPAM-1) is expressed on the majority of peripheral lymphocytes, on small subsets of thymocytes, and bone marrow progenitors. LPAM-1 binds to several ligands, VCAM-1, MAdCAM-1 and fibronectin, and is involved in lymphocyte adhesion and some hematopoietic progenitor cells migration. αE/β7 (CD103/β7,αIEL/β7) is expressed on intestinal intraepithelial lymphocytes (IEL), dendritic epidermal T cells, T regulatory cells, a subset of CD8+ T cells in lymph nodes and lamina propria. CD103/β7 complex is thought to play a role in lymphocyte retention via interaction with its ligand E-Cadherin.
    途径
    Integrin Complex
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