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CD93 抗体 (PE)

CD93 适用: 小鼠 WB, FACS 宿主: 大鼠 Monoclonal AA4-1 PE
产品编号 ABIN2663653
发货至: 中国
  • 抗原 See all CD93 抗体
    CD93
    适用
    • 59
    • 30
    • 30
    • 3
    小鼠
    宿主
    • 49
    • 16
    • 4
    大鼠
    克隆类型
    • 50
    • 19
    单克隆
    标记
    • 21
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    • 2
    • 1
    • 1
    • 1
    • 1
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    This CD93 antibody is conjugated to PE
    应用范围
    • 34
    • 24
    • 17
    • 13
    • 13
    • 12
    • 8
    • 6
    • 6
    • 6
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    克隆位点
    AA4-1
    亚型
    IgG2b kappa
    Top Product
    Discover our top product CD93 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    CD93
    别名
    CD93 (CD93 产品)
    别名
    6030404G09Rik antibody, AA145088 antibody, AA4.1 antibody, AW555904 antibody, C1qr1 antibody, C1qrp antibody, Ly68 antibody, C1QR1 antibody, C1qR(P) antibody, C1qRP antibody, CDw93 antibody, ECSM3 antibody, MXRA4 antibody, dJ737E23.1 antibody, C1qRp antibody, CD93 antigen antibody, CD93 molecule antibody, Cd93 antibody, CD93 antibody
    物质类
    Chemical
    背景
    CD93 is a 130-140kD C-type lectin like type I transmembrane protein, also known as complement component 1, q subcomponent (C1qR1), C1qRp collectin receptor (C1qRp), or AA4 antigen. It is a receptor expressed on immature B lymphocytes, hematopoietic progenitors and stem cells in adult bone marrow, fetal liver, embryonic yolk sac. CD93 expression level on splenic immature/transitional B cells is much lower than in bone marrow. It is reinduced during plasma cell differentiation and plays an important role in maintaining plasma cells in bone marrow niches. Immature dendritic cells express CD93 and down-regulate this molecule upon maturation, suggesting a role in uptake of particles by DC. It is also expressed on monocytes, macrophages, and endothelial cells. Macrophages from CD93 (-/-) mice had a significant phagocytic defect in the clearance of apoptotic cells in vivo, indicating CD93 may contribute to the in vivo clearance of dying cells. Binding of CD93 to C1q remains controversial.
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